9783540280064 - dislocation and degradation of proteins from the endoplasmic reticulum (current topics in microbiology and immunology, band 300) (8 Ergebnisse)

Sprache: Englisch
Verlag: Springer, 2005
Serie: Current Topics in Microbiology and Immunology, Buch 13 von 322. Buch 13 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
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Sprache: Englisch
Verlag: Springer, 2005
Serie: Current Topics in Microbiology and Immunology, Buch 13 von 322. Buch 13 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
Anbieter: Romtrade Corp., STERLING HEIGHTS, MI, USARomtrade Corp.
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Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Sprache: Englisch
Verlag: Springer, 2005
Serie: Current Topics in Microbiology and Immunology, Buch 13 von 322. Buch 13 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
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Zustand: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | The present volume of Current Topics in Microbiology and Immunology c- tains seven chapters that illuminate various aspects of a protein¿s genesis and terminal fate in the endoplasmic reticulum (ER). This area is of immediate medical relevance and ha…s blossomed, to no small extent, because of the study of molecules central to the function of the immune system [immunogl- ulins, T cell receptors, major histocompatibility complex (MHC)-encoded products]. Similarly, the clever strategies used by bacteria or viruses to gain a foothold in the host and ensure their continued survival have uncovered altogether new cell biological principles. It is therefore ?tting that a special volume be devoted to the interplay between pathways of protein degradation in the ER and a wide variety of pathogens. The concept of quality control emerged with the appreciation that, in the case of multimeric glycoproteins, any unpaired glycoprotein subunit had great dif?culties leaving its site of synthesis¿the ER¿and was destroyed instead. Free immunoglobulin heavy chains were probably the earliest documented example of this kind, and were long known to cause pathology when their accumulation went unchecked. Increased knowledge of the biosynthetic pathways of glycoproteins allowed the identi?cation of the ER as an important site where such quality control decisions were made. The T cell receptor for antigen, long considered the paradigm of this mode of degradation, led the way in these early explorations.

Sprache: Englisch
Verlag: Springer, 2005
Serie: Current Topics in Microbiology and Immunology, Buch 13 von 322. Buch 13 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
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Sprache: Englisch
Verlag: Springer Berlin Heidelberg, 2005
Serie: Current Topics in Microbiology and Immunology, Buch 13 von 322. Buch 13 von 322 - Current Topics in Microbiology and Immunology
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Sprache: Englisch
Verlag: Springer Berlin Heidelberg, Springer Berlin Heidelberg, 2005
Serie: Current Topics in Microbiology and Immunology, Buch 13 von 322. Buch 13 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The present volume of Current Topics in Microbiology and Immunology c- tains seven chapters that illuminate various aspects of a protein's genesis and terminal fate in the endoplasmic reticulum (ER). This area is of immediate medical relevance and has bloss…omed, to no small extent, because of the study of molecules central to the function of the immune system [immunogl- ulins, T cell receptors, major histocompatibility complex (MHC)-encoded products]. Similarly, the clever strategies used by bacteria or viruses to gain a foothold in the host and ensure their continued survival have uncovered altogether new cell biological principles. It is therefore tting that a special volume be devoted to the interplay between pathways of protein degradation in the ER and a wide variety of pathogens. The concept of quality control emerged with the appreciation that, in the case of multimeric glycoproteins, any unpaired glycoprotein subunit had great dif culties leaving its site of synthesis-the ER-and was destroyed instead. Free immunoglobulin heavy chains were probably the earliest documented example of this kind, and were long known to cause pathology when their accumulation went unchecked. Increased knowledge of the biosynthetic pathways of glycoproteins allowed the identi cation of the ER as an important site where such quality control decisions were made. The T cell receptor for antigen, long considered the paradigm of this mode of degradation, led the way in these early explorations.

Sprache: Englisch
Verlag: Springer, 2005
Serie: Current Topics in Microbiology and Immunology, Buch 13 von 322. Buch 13 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
Anbieter: BUCHSERVICE / ANTIQUARIAT Lars Lutzer, Wahlstedt, DeutschlandBUCHSERVICE / ANTIQUARIAT Lars Lutzer
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Hardcover. Zustand: gut. 2005. Dislocation and Degradation of Proteins from the Endoplasmic Reticulum In deutscher Sprache. pages.

Sprache: Englisch
Verlag: Springer Verlag, 2006
Serie: Current Topics in Microbiology and Immunology, Buch 13 von 322. Buch 13 von 322 - Current Topics in Microbiology and Immunology
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Hardcover. Zustand: Brand New. 1st edition. 172 pages. 9.00x6.25x0.50 inches. In Stock.