Isbn: 9783540207887 - validation in chemical measurement (1 Ergebnisse)

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Validationofmeasurementmethodshasbeenusedforavery ciated measurement uncertainty The answer must be: no. longtimeinchemistry. Itismostlybasedontheexamination Therecanneverbeamechanismorrecipeforproducing - of a measurement procedure for its characteristics such as tomatically valid results because one can never eliminate precision, accuracy, selectivity, sensitivity, repeatability, re- theskills,theroleandtheresponsibilityoftheanalyst. producibility,detectionlimit,quanti cationlimitandmore. ISO 9000:2000, item 3. 8. 5 de nes validation as con r- When focussing on quality comparability and reliability mation by examination and provision of objective evidence in chemical measurement, the elds of interest to this Jour- that the requirements for an intended use are ful lled . The nal, one stumbles into various interpretations of the term revised edition of the VIM ( VIM3 ), is likely to ne-tune validation. It is one more example of a term which is used thisde nitionoftheconcept validation tobe con rmation sometimes very consistently, sometimes very loosely or in- through examination of a given item and provision of - deed ambiguously. Since the term is very common in the jective evidence that it ful lls the requirements for a stated chemical community, it is important that its meaning be intendeduse . nd clear. Turning to the 2 edition of the International Vo- Lookingatsimplepractice, manypeoplearelookingfor cabulary of Basic and General terms in Metrology (VIM) aformaldecisionthatagivenmeasurementmethod automat- (1993), surprisingly we do not nd a de nition. Webster s ically gives them valid i. e. reliable results. One wonders Dictionary of the English language (1992) tells us that val- what this has to do with stated intended use . Reliab- idation is making or being made valid . Obviously valida- ity clearly is a property of a measurement result.…