Isbn: 9781934115886 - riboswitches: methods and protocols (methods in molecular biology, 540, band 540) (5 Ergebnisse)

Zustand: New. A comprehensive and timely reference volume for basic and applied research on regulatory RNAsCovers a wide range of assay formats and systems from the computerized prediction of regulatory RNA elements to their detailed structure-function characte.

Hardcover. Zustand: Brand New. 1st edition. 366 pages. 10.50x7.75x1.00 inches. In Stock.

Zustand: New. This book provides comprehensive, up-to-date coverage of many methods used to study riboswitches and other RNAs involved in gene expression control. It focuses on mRNAs responding to small organic molecules and offers an expanded definition of a riboswitch. Editor(s): Serganov, Alexander. Series: Methods in Molecular Biology. Num Pages: 366 pages, 65 black & white illustrations, 1 black & white tables, biography. BIC Classification: PSAK; PSD. Category: (P) Professional & Vocational. Dimension: 260 x 193 x 25. Weight in Grams: 930. . 2009. Hardback. . . . . Books ship from the US and Ireland. …

Buch. Zustand: Neu. Neuware - The transfer of hereditary information from genes to proteins is one of the essential pr- esses in all living organisms on our planet. Some genes are expressed without modu- tion throughout the life of a cell, while many others require various degrees of control to precisely balance cellular metabolism with environmental conditions. For many years, researchers attributed this regulatory function to protein molecules, which can direct gene expression at multiple levels, in response to various input signals, and with different degrees of selectivity. Even when the control of gene expression was achieved via direct interactions between proteins and mRNAs, the active role was routinely assigned to p- teins, while RNAs were considered merely as recipient molecules. The discovery of RNA interference and multiple bacterial regulatory RNAs caused a shift from the perception of proteins as the predominant regulators of gene expression to the acknowledgement of the importance of RNAs in many regulatory circuits. Such a viewpoint received strong support several years ago after the discovery of riboswitches and related RNA sensors - mRNA regions capable of alternating their conformations in response to the presence of cellular metabolites and other physical or chemical cues. These classes of RNA pass on cellular and environmental information directly to transcription or translation machinery without the assistance of proteins. The riboswitches are commonly defined as evolutionarily conserved mRNA regions capable of specific binding to metabolite molecules, and, as a result, adopting a particular RNA conformation that modulates gene expression.…

Zustand: New. pp. xi + 366 65 Illus.