9781621823810 - combining human genetics and causal inference to understand human disease and development: a subject collection from cold spring harbor perspectives in medicine (5 Ergebnisse)
Combining Human Genetics and Causal Inference to Understand Human Disease and Development (Perspectives CSHL)
Davey Smith, George; Richmond, Rebecca; Pingault, Jean-Baptiste
Sprache: Englisch
Verlag: Cold Spring Harbor Laboratory Press, 2022
- Hardcover
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Combining Human Genetics and Causal Inference to Understand Human Disease and Development: A Subject Collection from Cold Spring Harbor Perspectives in Medicine
Smith, George Davey (Editor)/ Richmond, Rebecca (Editor)/ Pingault, Jean-baptiste (Editor)
Sprache: Englisch
Verlag: Cold Spring Harbor Laboratory Pr, 2022
- Hardcover
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Hardcover. Zustand: Brand New. 1st edition. 253 pages. 10.00x7.00x0.75 inches. In Stock.
Sprache: Englisch
Verlag: COLD SPRING HARBOR LABORATORY, 2022
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Zustand: New. KlappentextWritten and edited by experts in the field, this collection examines advances in causal inference approaches in human genetics and how they are being used to enhance our understanding of human development and disease. The cont.
Combining Human Genetics and Causal Inference to Understand Human Disease and Development (Perspectives CSHL)
Davey Smith, George; Richmond, Rebecca; Pingault, Jean-Baptiste
Sprache: Englisch
Verlag: Cold Spring Harbor Laboratory Press, 2022
- Hardcover
Anbieter: Majestic Books, Hounslow, Vereinigtes KönigreichMajestic Books
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Zustand: New.
Sprache: Englisch
Verlag: Cold Spring Harbor Laboratory Press Jan 2022, 2022
- Hardcover
Anbieter: AHA-BUCH GmbH, Einbeck, DeutschlandAHA-BUCH GmbH
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Buch. Zustand: Neu. Neuware - In human genetics, causal inference methods leverage large omics data sets and phenotypic information to decipher various cause-and-effect relationships in human health and disease (e.g., smoking and lung cancer). The focus of such work is typically on modifiable variables (e.g., behavior or environ…mental exposure) that impact disease onset, progression, and outcome. A better understanding of these variables can lead to interventions and therapeutics that have a desirable impact on public health. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines advances in causal inference approaches in human genetics and how they are being used to enhance our understanding of human development and disease. The contributors discuss family-based study designs for causal inference, including twin designs, adoption designs, and in vitro fertilization designs, that separate inherited factors from perinatal environmental exposures. They also review various types of Mendelian randomization--a population-based approach that is growing in utility and popularity--as well as their integration with family-based designs. The use of these approaches to investigate causal mechanisms in specific scenarios (e.g., maternal smoking during pregnancy and ADHD in offspring) is also covered. This volume is therefore an essential read for geneticists, epidemiologists, and all biomedical scientists and public health professionals dedicated to using genetic information to improve human health.
