9781621820093 - dna recombination (6 Ergebnisse)
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Hardcover. Zustand: Very Good. No Jacket. Former library book; May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend Less.
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Zustand: Sehr gut. Gebraucht - Sehr gut -Recombination mechanisms allow cells to break and reattach DNA sequences. They are important for repair of damaged DNA. They also help generate additional genetic diversity in sperm and eggs cells by mixing DNA sequences from maternal and paternal chromosomes. This volume explores the mol…ecular details of recombination and their roles in genome maintenance and meiosis. Gebundene Ausgabe, Größe: 23.2 x 16.7 x 2.8 cm.
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Zustand: Good. Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, but in good overall condition. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions.
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Zustand: New.
DNA Recombination
Kowalczykowski, Stephen (Editor)/ Hunter, Neil (Editor)/ Heyer, Wolf-dietrich (Editor)
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Hardcover. Zustand: Brand New. 1st edition. 549 pages. 10.00x7.00x1.00 inches. In Stock.
Sprache: Englisch
Verlag: Cold Spring Harbor Laboratory Press Nov 2015, 2015
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Buch. Zustand: Neu. Neuware - Homologous recombination involves the precise exchange of similar or identical nucleic acid sequences between two DNA molecules. This process directs the repair of many DNA lesions in somatic cells and generates genetic variation in sperm and egg cells during meiosis. It is a nearly universal biolog…ical process that is conserved from phage to humans. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology covers all aspects of recombinational DNA repair, meiotic recombination, and the regulation of these processes. The contributors examine the dozens of proteins that are involved in recombinational repair and the various pathways in which they are employed (e.g., gene conversion or break-induced replication). They also discuss how these proteins and pathways are strictly regulated to avoid genomic instability, which can lead to diseases such as cancer, and how they are coordinated with other nuclear processes (e.g., transcription and DNA replication). Meiotic recombination, the characteristics that distinguish it from recombinational repair, and effects of its dysregulation (e.g., aneuploidy) are also covered in depth. This volume is an indispensable reference for biochemists, molecular biologists, and cell biologists who want to understand how DNA recombination maintains genomic integrity in individual organisms and across generations.
