Cancer drug discovery and development - 9781603272667 - chemokine receptors in cancer (cancer drug discovery and development) (3 Ergebnisse)
- Hardcover
Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes KönigreichRia Christie Collections
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EUR 165,41
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Zustand: New. In.
Sprache: Englisch
Verlag: Humana Press, 2009
Serie: Buch 59 von 96 - Cancer Drug Discovery and Development
- Hardcover
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Zustand: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | Chemokine Receptors in Cancer summarizes the growing body of evidence that several chemokine receptors contribute to tumor behavior. Chemokine receptors were first identified on leukocytes and mediate directed migration of many host cells to sites of… ligand expression. It is now well established that most malignant cells also express one or more chemokine receptor. This book describes our current understanding regarding how chemokine receptors contribute to tumor cell migration as well as cell survival and proliferation. The function of chemokine receptors expressed on host cells including antitumor immune effector cells as well as angiostatic and angiogeneic functions of chemokines acting on endothelial cells are described. The role of chemokine receptors that act as decoy receptors is also summarized. The therapeutic potential and challenges of targeting chemokine receptors or cognate ligands is also addressed.
Sprache: Englisch
Verlag: Humana Press Inc., 2009
Serie: Buch 59 von 96 - Cancer Drug Discovery and Development
- Hardcover
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Zustand: New. Chemokines are a superfamily of low molecular weight cytokines. In humans, there are approximately 45 chemokines that bind to 19 G-protein-coupled receptors. This book reviews what we do and do not know about the role of chemokine receptors in cancer behavior. Editor(s): Fulton, Amy M. Series: Cancer Drug Discovery… and Development. Num Pages: 172 pages, 13 black & white illustrations, 7 black & white tables, biography. BIC Classification: MJCL. Category: (P) Professional & Vocational. Dimension: 241 x 160 x 17. Weight in Grams: 442. . 2009. Hardback. . . . . Books ship from the US and Ireland.
