Advances in experimental medicine and biology - 9781493948659 - gene therapy for hiv and chronic infections (advances in experimental medicine and biology, band 848) (3 Ergebnisse)
Sprache: Englisch
Verlag: Springer, 2016
Serie: Buch 65 von 490 - Advances in Experimental Medicine and Biology
- Softcover
Anbieter: AHA-BUCH GmbH, Einbeck, DeutschlandAHA-BUCH GmbH
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EUR 116,53
EUR 30,50 VersandVersand von Deutschland nach USAAnzahl: 1 verfügbar
Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book centers on gene therapy and gene transfer approaches to prevent or treat chronic virus infections. The main focus is on the Big Three: human immunodeficiency virus (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV). Ample anti-HIV… drugs are currently available in the clinic and the development of an effective combination therapy has dramatically improved the lifespan and quality of life of infected individuals. A similar trend can already be recognized for HBV and HCV: the development of multiple (directly acting) antiviral drugs and plans to control or even cure the infection. However, approaches that help prevent infection, or which provide long-lasting treatment (such as a cure) remain important goals. Immunization through gene transfer vehicles encoding immunogenic viral proteins shows promise in preventing infections with complex, highly variable, viruses such as HIV-1 or HCV. Gene therapy applications for virus infections have been discussed since the early 1990's. Whereas a true cure seems difficult to achieve for HIV-1 due to its intrinsic property to deposit its genome into that of the host, such attempts may be within reach for HCV where spontaneous viral clearance occurs in a small percentage of the infected individuals. The prospect of original gene therapy approaches may provide alternative ways to reach the same endpoint by, for example, silencing of CCR5 expression post-transcriptionally. Many alternative antiviral strategies have been developed based on a variety of novel molecular methods: e.g. ribozymes. Some studies have progressed towards pre-clinical animal models and a few antiviral gene therapies have progressed towards clinical trials. This book provides an overview of this rapidly progressing field, while focusing on the interface of gene therapy and immunology/vaccinology.
Sprache: Englisch
Verlag: Springer, 2016
Serie: Buch 65 von 490 - Advances in Experimental Medicine and Biology
- Softcover
Anbieter: preigu, Osnabrück, Deutschlandpreigu
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EUR 95,25
EUR 70,00 VersandVersand von Deutschland nach USAAnzahl: 5 verfügbar
Taschenbuch. Zustand: Neu. Gene Therapy for HIV and Chronic Infections | Ben Berkhout (u. a.) | Taschenbuch | xvi | Englisch | 2016 | Springer | EAN 9781493948659 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Gene Therapy for HIV and Chronic Infections (Advances in Experimental Medicine and Biology)
Berkhout, Ben (Editor) / Ertl, Hildegund C.J. (Editor) / Weinberg, Marc S. (Editor)
Sprache: Englisch
Verlag: Springer, 2016
Serie: Buch 65 von 490 - Advances in Experimental Medicine and Biology
- Softcover
Anbieter: Revaluation Books, Exeter, Vereinigtes KönigreichRevaluation Books
Verkäufer/-in kontaktierenVerkäufer/-in mit 5 SternenZustand: Neu
EUR 176,98
EUR 11,65 VersandVersand von Vereinigtes Königreich nach USAAnzahl: 1 verfügbar
Paperback. Zustand: Brand New. reprint edition. 252 pages. 9.25x6.10x0.60 inches. In Stock.
