9781493924318 - gene therapy for hiv and chronic infections (advances in experimental medicine and biology, 848, band 848) (4 Ergebnisse)
Sprache: Englisch
Verlag: Springer, 2015
Serie: Advances in Experimental Medicine and Biology, Buch 65 von 490. Buch 65 von 490 - Advances in Experimental Medicine and Biology
- Hardcover
Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes KönigreichRia Christie Collections
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Zustand: New. In.
Gene Therapy for HIV and Chronic Infections
Berkhout, Ben (Edited by)/ Ertl, MD, Hildegund CJ (Edited by)/ Weinberg, Marc S. (Edited by)
Sprache: Englisch
Verlag: Springer, 2015
Serie: Advances in Experimental Medicine and Biology, Buch 65 von 490. Buch 65 von 490 - Advances in Experimental Medicine and Biology
- Hardcover
Anbieter: Revaluation Books, Exeter, Vereinigtes KönigreichRevaluation Books
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EUR 156,15
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Hardcover. Zustand: Brand New. 1st edition. 236 pages. 9.50x6.00x0.75 inches. In Stock.
Sprache: Englisch
Verlag: Springer New York, Springer US, 2015
Serie: Advances in Experimental Medicine and Biology, Buch 65 von 490. Buch 65 von 490 - Advances in Experimental Medicine and Biology
- Hardcover
Anbieter: AHA-BUCH GmbH, Einbeck, DeutschlandAHA-BUCH GmbH
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EUR 112,94
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book centers on gene therapy and gene transfer approaches to prevent or treat chronic virus infections. The main focus is on the Big Three: human immunodeficiency virus (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV). Ample anti-HIV drugs…are currently available in the clinic and the development of an effective combination therapy has dramatically improved the lifespan and quality of life of infected individuals. A similar trend can already be recognized for HBV and HCV: the development of multiple (directly acting) antiviral drugs and plans to control or even cure the infection. However, approaches that help prevent infection, or which provide long-lasting treatment (such as a cure) remain important goals. Immunization through gene transfer vehicles encoding immunogenic viral proteins shows promise in preventing infections with complex, highly variable, viruses such as HIV-1 or HCV. Gene therapy applications for virus infections have been discussed since the early 1990's. Whereas a true cure seems difficult to achieve for HIV-1 due to its intrinsic property to deposit its genome into that of the host, such attempts may be within reach for HCV where spontaneous viral clearance occurs in a small percentage of the infected individuals. The prospect of original gene therapy approaches may provide alternative ways to reach the same endpoint by, for example, silencing of CCR5 expression post-transcriptionally. Many alternative antiviral strategies have been developed based on a variety of novel molecular methods: e.g. ribozymes. Some studies have progressed towards pre-clinical animal models and a few antiviral gene therapies have progressed towards clinical trials. This book provides an overview of this rapidly progressing field, while focusing on the interface of gene therapy and immunology/vaccinology.
Sprache: Englisch
Verlag: Springer New York, 2015
Serie: Advances in Experimental Medicine and Biology, Buch 65 von 490. Buch 65 von 490 - Advances in Experimental Medicine and Biology
- Hardcover
Anbieter: Buchpark, Trebbin, DeutschlandBuchpark
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EUR 83,44
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Zustand: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | This book centers on gene therapy and gene transfer approaches to prevent or treat chronic virus infections. The main focus is on the Big Three: human immunodeficiency virus (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV). Ample anti-HI…V drugs are currently available in the clinic and the development of an effective combination therapy has dramatically improved the lifespan and quality of life of infected individuals. A similar trend can already be recognized for HBV and HCV: the development of multiple (directly acting) antiviral drugs and plans to control or even cure the infection. However, approaches that help prevent infection, or which provide long-lasting treatment (such as a cure) remain important goals. Immunization through gene transfer vehicles encoding immunogenic viral proteins shows promise in preventing infections with complex, highly variable, viruses such as HIV-1 or HCV. Gene therapy applications for virus infections have been discussed since the early 1990¿s. Whereas a true cure seems difficult to achieve for HIV-1 due to its intrinsic property to deposit its genome into that of the host, such attempts may be within reach for HCV where spontaneous viral clearance occurs in a small percentage of the infected individuals. The prospect of original gene therapy approaches may provide alternative ways to reach the same endpoint by, for example, silencing of CCR5 expression post-transcriptionally. Many alternative antiviral strategies have been developed based on a variety of novel molecular methods: e.g. ribozymes. Some studies have progressed towards pre-clinical animal models and a few antiviral gene therapies have progressed towards clinical trials. This book provides an overview of this rapidly progressing field, while focusing on the interface of gene therapy and immunology/vaccinology.
