Isbn: 9781118916698 - oral bioavailability assessment: basics and strategies for drug discovery and development (wiley series on pharmaceutical science) (5 Ergebnisse)

Zustand: New. In English.

Zustand: New. Ayman F. El-Kattan, B. Pharm, PhD, is Associate Research Fellow in Pfizer s Pharmacokinetics, Dynamics, and Metabolism Department, Cambridge Laboratories and an Adjunct Professor at College of Pharmacy-University of Rhode Island in Rhode Island, US. Dr. El-.

Zustand: New. Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability one of the most significant hurdles in drug discovery and development. Series Editor(s): Lee, Mike S. Series: Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods. Num Pages: 464 pages. BIC Classification: TCB; TDCW. Category: (P) Professional & Vocational. Weight in Grams: 666. . 2017. 1st Edition. hardcover. . . . . Books ship from the US and Ireland.…

Hardcover. Zustand: Brand New. 1st edition. 436 pages. 9.50x6.25x1.25 inches. In Stock.

Buch. Zustand: Neu. Neuware - Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability - one of the most significant hurdles in drug discovery and development.- Describes approaches to assess pharmacokinetics and how drug efflux and uptake transporters impact oral bioavailability- Helps readers reduce the failure rate of drug candidates when transitioning from the bench to the clinic during development- Explains how preclinical animal models - used in preclinical testing - and in vitro tools translate to humans, which is an underappreciated and complicated area of drug development- Includes chapters about pharmacokinetic modelling, the Biopharmaceutics Drug Disposition Classification System (BDDCS), and the Extended Clearance Classification System (ECCS)- Has tutorials for applying strategies to medicinal chemistry practices of drug discovery/development.…