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In den WarenkorbZustand: Used. pp. 664.
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Taschenbuch. Zustand: Neu. Gene Therapy of Cancer | Methods and Protocols | Ulrike Stein (u. a.) | Taschenbuch | xvi | Englisch | 2000 | Humana Press | EAN 9780896038431 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
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EUR 155,25
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In den WarenkorbPlastic Comb. Zustand: Brand New. spiral-bound edition. 645 pages. 9.25x6.50x1.25 inches. In Stock.
Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 664 | Sprache: Englisch | Produktart: Bücher | Since the discovery of the molecular structure of genes and the unveiling of the molecular basis of numerous human diseases, scientists have been fas- nated with the possibility of treating certain diseases by transducing foreign DNA into the affected cells. Initially, it was proposed that the foreign DNA could either replace defective nonfunctional genes, or code for therapeutic proteins. This concept has evolved into the rapidly growing field of gene therapy. Even though surgery, radiotherapy, and chemotherapy are widely ava- able and routinely used for cancer treatment, these therapies fail to cure approximately 50 percent of cancer patients. Therefore, since it is a disease characterized by aberrant gene expression, cancer has been a target of gene therapy research since the inception of this treatment modality. Numerous cancer gene therapy strategies are currently being investigated, including gene replacement therapy, the regulation of gene expression to modulate immu- logical responses to tumors, the direct killing of tumor cells, and direct int- ference with tumor growth. In this context, gene transfer systems, tumor-specific expression vectors, and novel therapeutic genes have been extensively st- ied. All these strategies aim for the selective destruction of human malignant disease while circumventing the destruction of nonmalignant cells and tissues thereby minimizing toxicity to the patient.