Isbn: 9780896032750 - antibody engineering protocols (methods in molecular biology, 51, band 51) (6 Ergebnisse)

Spiralbuch. Zustand: Gut. 450 Seiten Der Erhaltungszustand des hier angebotenen Werks ist trotz seiner Bibliotheksnutzung sehr sauber. Es befindet sich neben dem Rückenschild lediglich ein Bibliotheksstempel im Buch; ordnungsgemäß entwidmet. In ENGLISCHER Sprache. Sprache: Englisch Gewicht in Gramm: 600. …

Zustand: New. In English.

Zustand: New. This collection of developed methods for producing new antibody reagents by immunization and recombinant DNA techniques contains ready-to-use protocols that illuminate current areas of research on antibody structure. It aims to minimize extensive literature and methodology searches. Series: Methods in Molecular Biology. Num Pages: 450 pages, biography. BIC Classification: MJCM; PSD; TCB. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 23. Weight in Grams: 661. . 1995. Paperback. . . . . Books ship from the US and Ireland. …

Kartoniert / Broschiert. Zustand: New. SEQHUNT: A Program to Screen Aligned Nucleotide and Amino Acid Sequences. Molecular Modeling of Antibody-Combining Sites. Structure and Properties of Human Immunoglobulin Light-Chain Dimers. Crystallographic and Chromatographic Methods for Study of Antibody.

Taschenbuch. Zustand: Neu. Neuware - Antibodies are the instraments of immune defense and attack. They can bind small atomic arrays as well as large epitopes with high affinity. Antibody Engineering Protocols presents advanced protocols in the field of antibody engineering, reviews of basic principles and methodology, and a historical perspective on the development of cur rently held beliefs about antibody structure-function relationships. The topics cover analysis of antibody sequences, three-dimensional structure, delineation of antibody characteristics in polyclonal mixtures, phage display of natural and synthetic antibodies, and antibody catalysis. Ligand recognition by antibodies occurs primarily at a subset of amino acid residues located in the complementarity determining regions (CDRs) found in the light (L) and heavy (H) chain subunits. Specific antibodies are developed by immunization with molecules identical to or related in structure to the target ligand. The immune repertoire from nonimmunized individuals also contains pre-existing specificities that can be selected by screening libraries composed of hybridoma cells or phage particles displaying F domains or indi vidual variable domains of the light (VJ and heavy (V^^) chains. Ran dom or site-directed mutagenesis in vitro can be used to refine the pre-existing specificities or produce new specificities de novo. Another level at which new specificities may be generated in vitro is V^ and V^ domain-swapping and CDR-swapping. The former procedure embodies a variation of natural mechanisms of generating antibody diversity. The latter procedure produces new intramolecular CDR combinations not found in nature.…

Zustand: gut. 1995. Antibody Engineering Protocols (Methods in Molecular Biology, Band 51) In englischer Sprache. pages.