Isbn: 9780470631324 - applications of transition metal catalysis in drug discovery and development: an industrial perspective (8 Ergebnisse)

HRD. Zustand: New. New Book. Shipped from UK. Established seller since 2000.

Zustand: New. In English.

Zustand: New. pp. 376.

Hardcover. Zustand: Brand New. 1st edition. 376 pages. 9.29x6.22x1.02 inches. In Stock.

Zustand: New. The book will be particularly appreciated by young scientists, especially those aspiring to a future in the pharmaceutical industry, because it shows what kind of problems they will be asked to solve once they start their industrial career. (ChemMedChem, .

Zustand: New. This book documents examples of transition metal catalysis in drug discovery and development from an industrial perspective. Co-edited by Barry Trost, one of the foremost organic research chemists, the authors pay particular attention to transitioning academically-developed reactions into scalable industrial processes. Editor(s): Crawley, Matthew L.; Trost, Barry M. Num Pages: 376 pages, Illustrations. BIC Classification: PNN; TDCW. Category: (P) Professional & Vocational. Dimension: 236 x 163 x 25. Weight in Grams: 666. . 2012. 1st Edition. Hardcover. . . . . Books ship from the US and Ireland.…

Buch. Zustand: Neu. Neuware - This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development - it is a guide, a historical prospective, a practical compendium, and a source of future direction for the field. Lays the groundwork for developing promising new drug candidatesDrawing on real-life examples, this book demonstrates the applications of transition metal catalysis in drug discovery and development, and its role in the efficient creation of both preclinical and clinical drug candidates as well as commercialized drugs. The authors pay particular attention to the challenges of transitioning reactions developed in academic labs into scalable industrial processes.Applications of Transition Metal Catalysis in Drug Discovery and Development begins with a general overview of the use of transition metal catalysis in the pharmaceutical industry. Next, it covers:Transition metal-catalyzed carbon-carbon cross-coupling reactionsPalladium- and copper-catalyzed carbon-heteroatom cross-coupling reactionsAsymmetric cross-coupling reactions and metathesisTransition metal-catalyzed synthesis of five- and six-membered heterocyclesOxidative catalysis and industrial asymmetric hydrogenationBoth the editors and authors are internationally recognized experts in drug discovery and development. All authors are scientists from such major pharmaceutical companies as Boehringer Ingelheim, GlaxoSmithKline, Merck, Amgen, and Novartis. Additionally, many of the authors have been responsible for developing the reactions and the drugs discussed in the book, providing readers with firsthand accounts of their discoveries.This remarkable work serves as a guide, historical perspective, and practical compendium, offering pharmaceutical researchers and medicinal chemists a unique perspective on the applications of transition metal catalysis in drug discovery and development. Moreover, the book lays the groundwork for continued development of transition metal-catalyzed processes, setting the stage for new and promising drug candidates.…

Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 384 | Sprache: Englisch | Produktart: Bücher | Lays the groundwork for developing promising new drug candidates Drawing on real-life examples, this book demonstrates the applications of transition metal catalysis in drug discovery and development, and its role in the efficient creation of both preclinical and clinical drug candidates as well as commercialized drugs. The authors pay particular attention to the challenges of transitioning reactions developed in academic labs into scalable industrial processes. Applications of Transition Metal Catalysis in Drug Discovery and Development begins with a general overview of the use of transition metal catalysis in the pharmaceutical industry. Next, it covers: Transition metal-catalyzed carboncarbon cross-coupling reactions Palladium- and copper-catalyzed carbonheteroatom cross-coupling reactions Asymmetric cross-coupling reactions and metathesis Transition metal-catalyzed synthesis of five- and six-membered heterocycles Oxidative catalysis and industrial asymmetric hydrogenation Both the editors and authors are internationally recognized experts in drug discovery and development. All authors are scientists from such major pharmaceutical companies as Boehringer Ingelheim, GlaxoSmithKline, Merck, Amgen, and Novartis. Additionally, many of the authors have been responsible for developing the reactions and the drugs discussed in the book, providing readers with firsthand accounts of their discoveries. This remarkable work serves as a guide, historical perspective, and practical compendium, offering pharmaceutical researchers and medicinal chemists a unique perspective on the applications of transition metal catalysis in drug discovery and development. Moreover, the book lays the groundwork for continued development of transition metal-catalyzed processes, setting the stage for new and promising drug candidates.…