9780375502446 - Dr. Folkman's War: Angiogenesis and the Struggle to Defeat Cancer von Cooke, Robert (14 Ergebnisse)

Zustand: Acceptable. Item in acceptable condition! Textbooks may not include supplemental items i.e. CDs, access codes etc.

Zustand: Good. Item in good condition. Textbooks may not include supplemental items i.e. CDs, access codes etc.

Zustand: good. Gently used with minimal wear on the corners and cover. A few pages may contain light highlighting or writing, but the text remains fully legible. Dust jacket may be missing, and supplemental materials like CDs or codes may not be included. May be ex-library with library markings. Ships promptly!

Hardcover. Zustand: As New. No Jacket. Pages are clean and are not marred by notes or folds of any kind. ~ ThriftBooks: Read More, Spend Less.

Hardcover. Zustand: Very Good. 1. With dust jacket. It's a well-cared-for item that has seen limited use. The item may show minor signs of wear. All the text is legible, with all pages included. It may have slight markings and/or highlighting.

Zustand: Good. Good condition. Good dust jacket. A copy that has been read but remains intact. May contain markings such as bookplates, stamps, limited notes and highlighting, or a few light stains.

Zustand: Good. 1st Edition. Pages intact with minimal writing/highlighting. The binding may be loose and creased. Dust jackets/supplements are not included. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.

Zustand: Very Good. 1st Edition. Former library copy. Pages intact with possible writing/highlighting. Binding strong with minor wear. Dust jackets/supplements may not be included. Includes library markings. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.

Paperback. Zustand: Very Good. The book has been read, but is in excellent condition. Pages are intact and not marred by notes or highlighting. The spine remains undamaged.

hardcover. Zustand: very good(+). Zustand des Schutzumschlags: very good(+). First. Foreword by Dr. C. Everett Koop. Illustrated. xiv + 366 pages, 8vo, boards, d.w. New York: Random House, (2001). First edition. A very good(+) copy in a very good(+) dust wrapper.

Hardcover. First edition. Stated. xiv, 384 p. Illustrations. index. Foreword by C. Everett Koop. This controversial story details the work of Dr. Judah Folkman, a pioneer in the cancer research field. Through interviews, research, and laboratory records, a science journalist traces Folkman's success with treating cancer in mice--reported in The New York Times in a 1998 article heavily criticized for prematurely claiming a cure. Emphasizing the two subsequent years of successful clinical trials in humans, this book argues for a renewed discussion of Folkman's work as a potential cure for cancer. Very good in very good dust jacket. DJ has slight wear and soiling, with small edge wear and sticker residue.

Hardcover. Zustand: Brand New. 1st edition. 366 pages. 9.50x6.50x1.25 inches. In Stock.

Hardcover. Zustand: New. In 1961, twenty-eight-year-old Dr. Judah Folkman saw something while doing medical research in a United States navy lab that gave him the first glimmering of a wild, inspired hunch. What if cancerous tumors, in order to expand, needed to trigger the growth of new blood vessels to feed themselves? And if that was true, what if a way could be found to stop that growth? Could cancers be starved to death? Dr. Folkman had ample reason to be self confident second in his class at Harvard Medical School, he was already considered one of the most promising doctors of his generation. But even he never guessed that his idea would eventually grow into a multibillion-dollar industry that is now racing through human trials with drugs that show unparalleled promise of being able to control cancer, as well as other deadly diseases. For the creation of this book, Dr. Judah Folkman cooperated fully and exclusively with acclaimed science writer Robert Cooke. He granted Cooke unlimited interviews, showed him diaries and personal papers, and threw open the doors of his lab. The result is an astonishingly rich and candid chronicle of one of the most significant medical discoveries of our time and of the man whose vision and persistence almost single-handedly has made it possible. Dr. Folkman's radical new way of thinking about cancer was once considered preposterous. So little was known about how cancer spreads and how blood vessels grow that he wasn't even taken seriously enough to be considered a heretic. Other doctors shook their heads at the waste of a great mind, and ambitious young medical researchers were told that accepting a position in Folkman's lab would be the death of their careers. Now, though, the overwhelming majority of experts believes that the day will soon come when antiangiogenesis therapy supplants the current more toxic and less-effective treatments chemotherapy, radiation, and surgery-as the preferred method of treatment for cancer in patients around the world, and Dr. Folkman's breakthrough will come to be taken for granted the way we now take for granted the polio vaccine and antibiotics. Dr. Folkman's Warbrilliantly describes how high the odds are against success in medical research, how vicious the competition for grants, how entrenched the skepticism about any genuinely original thinking, how polluted by politics and commerce the process of getting medicine into patients' hands. But it also depicts with rare power how exalted a calling medicine can be and how for the rare fewthe brilliant, the tireless, and the lucky the results of success can be world-changing.

Hardcover. Zustand: Very good. Zustand des Schutzumschlags: Very good. Bill Greene (Jacket Photo) (illustrator). First Edition [stated]. xiv, [3], 366, [2] pages. Index. DJ has slight wear and soiling. Inscribed by the author, Robert Cooke, on the front free endpaper. Inscription reads: Tom, I Hope you find this is a good read. There's much more to come. Robert Coke, 5/2001; Also inscribed by Judah Folkman, May 2001. Inscription reads To Tom, I appreciate your request about my papers. Judah Folkman, May 2001. Sticker inside back cover indicates this once belonged to Tom Horrocks. Includes Foreword by C. Everett Koop, M.D. Also includes Acknowledgments and Index. Moses Judah Folkman (February 24, 1933 - January 14, 2008) was an American medical scientist best known for his research on tumor angiogenesis, the process by which a tumor attracts blood vessels to nourish itself and sustain its existence. He founded the field of angiogenesis research, which has led to the discovery of a number of therapies based on inhibiting or stimulating neovascularization. In 2004, the first angiogenesis inhibitor, bevacizumab (Avastin), was approved by the FDA, as a treatment for colon cancer. For his discoveries which originated the concept and developed the field of angiogenesis research, Folkman was awarded the Wolf Prize in Medicine in 1992. He was awarded the Massry Prize from the Keck School of Medicine, University of Southern California in 1997. This book brilliantly describes how high the odds are against success in medical research, how vicious the competition for grants, how entrenched the skepticism about any genuinely original thinking, how polluted by politics and commerce the process of getting medicine into patients' hands. But it also depicts with rare power how exalted a calling medicine can be and how for the rare few--the brilliant, the tireless, and the lucky--the results of success can be world changing. Judah Folkman's answer--stop cancers by cutting off their blood supplies--has much too long been thought of as too simple to ever work. Now, however, a broad set of antiangiogenic agents based on Judah's ideas are coming in line. The verdict 'cancer' need no longer be synonymous with fear and despair. Our country's "war against cancer'' at last has found its general. In 1961, twenty-eight-year-old Dr. Judah Folkman saw something while doing medical research in a United States navy lab that gave him the first glimmering of a wild, inspired hunch. What if cancerous tumors, in order to expand, needed to trigger the growth of new blood vessels to feed themselves? And if that was true, what if a way could be found to stop that growth? Could cancers be starved to death? Dr. Folkman had ample reason to be self confident second in his class at Harvard Medical School, he was already considered one of the most promising doctors of his generation. But even he never guessed that his idea would eventually grow into a multibillion-dollar industry that is now racing through human trials with drugs that show unparalleled promise of being able to control cancer, as well as other deadly diseases. For the creation of this book, Dr. Judah Folkman cooperated fully and exclusively with acclaimed science writer Robert Cooke. He granted Cooke unlimited interviews, showed him diaries and personal papers, and threw open the doors of his lab. The result is an astonishingly rich and candid chronicle of one of the most significant medical discoveries of our time and of the man whose vision and persistence almost single-handedly has made it possible. Dr. Folkman's radical new way of thinking about cancer was once considered preposterous. So little was known about how cancer spreads and how blood vessels grow that he wasn't even taken seriously enough to be considered a heretic. Other doctors shook their heads at the waste of a great mind, and ambitious young medical researchers were told that accepting a position in Folkman's lab would be the death of their careers. Now, though, the overwhelming majority of experts believes that the day will soon come when antiangiogenesis therapy supplan.