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Zustand: New. Identifies methods to facilitate development of corresponding animal and clinical endpoints, indentifies methods that would maximize bidirectional translation between basic and clinical research and determines the next steps that can be critical for improvement of the development and testing of animal models of disorders of the nervous system. Editor(s): Pankevich, Diana E.; Wizemann, Theresa M.; Altevogt, Bruce M. Num Pages: 110 pages, illustrations. BIC Classification: MBGL; MJN. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 0. . . 2013. Paperback. . . . . Books ship from the US and Ireland.
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Zustand: New. Identifies methods to facilitate development of corresponding animal and clinical endpoints, indentifies methods that would maximize bidirectional translation between basic and clinical research and determines the next steps that can be critical for improve.
Sprache: Englisch
Verlag: National Academies Press Apr 2013, 2013
ISBN 10: 0309266335 ISBN 13: 9780309266338
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Taschenbuch. Zustand: Neu. Neuware - Nervous system diseases and disorders are highly prevalent and substantially contribute to the overall disease burden. Despite significant information provided by the use of animal models in the understanding of the biology of nervous system disorders and the development of therapeutics; limitations have also been identified. Treatment options that are high in efficacy and low in side effects are still lacking for many diseases and, in some cases are nonexistent. A particular problem in drug development is the high rate of attrition in Phase II and III clinical trials. Why do many therapeutics show promise in preclinical animal models but then fail to elicit predicted effects when tested in humans.
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Taschenbuch. Zustand: Neu. Improving the Utility and Translation of Animal Models for Nervous System Disorders | Workshop Summary | Board On Health Sciences Policy (u. a.) | Taschenbuch | Englisch | 2013 | National Academies Press | EAN 9780309266338 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu.