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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - A mathematician who has taken the romantic decision to devote himself to biology will doubtlessly look upon cell kinetics as the most simple and natural field of application for his knowledge and skills. Indeed, the thesaurus he is to master is not so complicated as, say, in molecular biology, the structural elements of the system, i. e. ceils, have been segregated by Nature itself, simple considerations of balance may be used for deducing basic equations, and numerous analogies in other areas of science also superficial add to one's confidence. Generally speaking, this number of impression is correct, as evidenced by the very great theoretical studies on population kinetics, unmatched in other branches of mathematical biology. This, however, does not mean that mathematical theory of cell systems has traversed in its development a pathway free of difficulties or errors. The seeming ease of formalizing the phenomena of cell kinetics not infrequently led to the appearance of mathematical models lacking in adequacy or effectiveness from the viewpoint of applications. As in any other domain of science, mathematical theory of cell systems has its own intrinsic logic of development which, however, depends in large measure on the progress in experimental biology. Thus, during a fairly long period running into decades activities in that sphere were centered on devising its own specific approaches necessitated by new objectives in the experimental in vivo and in vitro investigation of cell population kinetics in different tissues.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The search for ways to overcome tumour radioresistance is a major problem of experimental and clinical radiation oncology. The diffi culties involved in the attempts to solve this problem are a matter of common knowledge. In many a laboratory extensive studies are un derway of factors determining tumour tissue response to irradiation and of methods for exerting directional effect upon those factors. Such studies have revealed that, at least at the cellular level, a considerable number of factors manifest themselves which are respon sible for radiation effect (1] Among those are: spatial heteroge neity of tumour cell population producing radioresistant cell reser ves (hypoxic cells of solid tumours); differing radiosensitivities of cell life cycle phases; intrinsic dynamics of the processes of radi ation damage and postradiation cell recovery; induction of prolifera tive processes in response to the death of some cells within the po pulation; the stochastic nature of cell kinetics and complicated in teraction between individual cell subpopulations corresponding to di fferent tumour loci. Questions arise as to whether the researchers are now in possession of adequate means for interpreting experimental findings and clinical evidence and whether there are procedures for performing complex analysis and predicting specific tumour responses to various irradiation regimens and to combined antitumoral effects, taking into account the complexities of the phenomena under study.

Zustand: New. In.

Zustand: New. In.

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Paperback. Zustand: Brand New. 1988 edition. 140 pages. 9.01x5.98x0.32 inches. In Stock.

Paperback. Zustand: Brand New. illustrated edition. 220 pages. 9.61x6.69x0.53 inches. In Stock.