toivonen hannu (15 Ergebnisse)

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Zustand: New. pp. 356 Illus.

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paperback. Zustand: Gut. Seiten; 9783540440376.3 Gewicht in Gramm: 1.

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Zustand: New. pp. 552 Illus.

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Paperback. Zustand: Brand New. 2002 edition. 514 pages. 10.25x6.00x1.00 inches. In Stock.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - We are pleased to present the proceedings of the 13th European Conference on Machine Learning (LNAI 2430) and the 6th European Conference on Principles and Practice of Knowledge Discovery in Databases (LNAI 2431). These two c- ferences were colocated in Helsinki, Finland during August 19 23, 2002. ECML and PKDD were held together for the second year in a row, following the success of the colocation in Freiburg in 2001. Machine learning and knowledge discovery are two highly related elds and ECML/PKDD is a unique forum to foster their collaboration. The bene t of colocation to both the machine learning and data mining communities is most clearly displayed in the common workshop, tutorial, and invited speaker program. Altogether six workshops and six tutorials were or- nized on Monday and Tuesday. As invited speakers we had the pleasure to have Erkki Oja (Helsinki Univ. of Technology), Dan Roth (Univ. of Illinois, Urbana- Champaign), Bernhard Sch olkopf (Max Planck Inst. for Biological Cybernetics, T ubingen), and Padhraic Smyth (Univ. of California, Irvine). The main events ran from Tuesday until Friday, comprising 41 ECML te- nical papers and 39 PKDD papers. In total, 218 manuscripts were submitted to these two conferences: 95 to ECML, 70 to PKDD, and 53 as joint submissions. All papers were assigned at least three reviewers from our international program committees. Out of the 80 accepted papers 31 were rst accepted conditi- ally; the revised manuscripts were accepted only after the conditions set by the reviewers had been met.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book constitutes the refereed preceedings of the 13th European Conference on Machine Learning, ECML 2002, held in Helsinki, Finland in August 2002.The 41 revised full papers presented together with 4 invited contributions were carefully reviewed and selected from numerous submissions. Among the topics covered are computational discovery, search strategies, Classification, support vector machines, kernel methods, rule induction, linear learning, decision tree learning, boosting, collaborative learning, statistical learning, clustering, instance-based learning, reinforcement learning, multiagent learning, multirelational learning, Markov decision processes, active learning, etc.

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Gebunden. Zustand: New. No known book on this areaFirst book containing the work of key researchers in biological data miningPresents new techniques on (a) gene expression data mining, (b) gene mapping for disease detection, and (c) phylogenetic knowledge discover.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - 8. 1. 1 Protein Subcellular Location The life sciences have entered the post-genome era where the focus of biologicalresearchhasshiftedfromgenomesequencestoproteinfunctionality. Withwhole-genomedraftsofmouseandhumaninhand,scientistsareputting more and more e ort into obtaining information about the entire proteome in a given cell type. The properties of a protein include its amino acid sequences, its expression levels under various developmental stages and in di erenttissues,its3Dstructureandactivesites,itsfunctionalandstructural binding partners, and its subcellular location. Protein subcellular location is important for understanding protein function inside the cell. For example, the observation that the product of a gene is localized in mitochondria will support the hypothesis that this protein or gene is involved in energy metabolism. Proteins localized in the cytoskeleton are probably involved in intracellular tra cking and support. The context of protein functionality is well represented by protein subcellular location. Proteins have various subcellular location patterns [250]. One major category of proteins is synthesized on free ribosomes in the cytoplasm. Soluble proteins remain in the cytoplasm after their synthesis and function as small factories catalyzing cellular metabolites. Other proteins that have a target signal in their sequences are directed to their target organelle (such as mitochondria) via posttranslational transport through the organelle membrane. Nuclear proteins are transferred through pores on the nuclear envelope to the nucleus and mostly function as regulators. The second major category of proteins is synthesized on endoplasmic reticulum(ER)-associated ribosomes and passes through the reticuloendothelial system, consisting of the ERand the Golgi apparatus.