springer timothy (13 Ergebnisse)

gebundene Ausgabe. Zustand: Gut. 287 Seiten; Der Erhaltungszustand des hier angebotenen Werks ist trotz seiner Bibliotheksnutzung sehr sauber. Es befindet sich neben dem Rückenschild lediglich ein Bibliotheksstempel im Buch; ordnungsgemäß entwidmet. Sprache: Englisch Gewicht in Gramm: 650.

Zustand: Good. 602 pp., Hardcover, ex library, else text and binding clean and tight. - If you are reading this, this item is actually (physically) in our stock and ready for shipment once ordered. We are not bookjackers. Buyer is responsible for any additional duties, taxes, or fees required by recipient's country.

Zustand: New. pp. 287.

Gebundene Ausgabe. Zustand: Gut. 602 Seiten ex Library Book aus einer wissentschaftlichen Bibliothek Sprache: Englisch Gewicht in Gramm: 550.

Zustand: New. In.

Paperback. Zustand: Brand New. 302 pages. 9.25x6.10x0.63 inches. In Stock.

Taschenbuch. Zustand: Neu. Leukocyte Adhesion Molecules | Proceedings of the First International Conference on: "Structure, Function and Regulation of Molecules Involved in Leukocyte Adhesion", Held in Titisee, West Germany, September 28 - October 2, 1988 | Timothy A. Springer (u. a.) | Taschenbuch | xv | Englisch | 2011 | Springer | EAN 9781461279273 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Leukocyte adhesion molecules promise to be highly effective as antigens in the antibody-directed leucocyte elimination treatment prior to grafting or in cases of acute and chronic inflammatory disease. This comprehensive review of contemporary research provides thorough discussions of the structure of these molecules, their in vitro function, and the role that they play in vivo as evidenced by results shown in inflammatory models where antibodies against these molecules are given to inhibit their function. The blend of basic science and clinical applications provides clear evidence of the biological relevance of cell-cell interactions and the many potential clinical dividends afforded by understanding the molecular basis of cell adhesion.

Zustand: New. In.

Taschenbuch. Zustand: Neu. Hybridoma Technology in the Biosciences and Medicine | Timothy Springer | Taschenbuch | xxv | Englisch | 2012 | Springer | EAN 9781468449662 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Paperback. Zustand: Brand New. reprint edition. 627 pages. 9.45x6.61x1.43 inches. In Stock.

Hardcover. Zustand: Brand New. har/psc edition. 393 pages. 11.00x8.75x1.00 inches. In Stock.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - InhaltsangabeI. The Production and Improvement through Genetic Engineering of Monoclonal Antibodies.- 1. Monoclonal Antibody Strategy and Techniques.- 1. Introduction.- 2. Factors That Control Immunogenicity.- 3. Strategy and Tactics for the Preparation of Monoclonal Antibodies.- 4. Procedures for the Production of Monoclonal Antibodies.- 5. Screening Assays for Monoclonal Antibody.- References.- 2. Strategies for Production of Human Monoclonal Antibodies.- 1. Introduction.- 2. Human versus Mouse Monoclonal Antibodies.- 3. Epstein-Barr Virus.- 4. Human Hybridomas. Fusion Partners.- 5. Epstein-Barr Virus Hybridoma Technique.- 6. Large-Scale Production of Human Monoclonal Antibodies.- 7. Possible Limitations and Future Developments.- References.- 3. The Antibody Combining Site.- 1. Introduction.- 2. Structure of the Antibody Combining Site.- 3. Digoxin-Specific Monoclonal Antibodies.- 4. A Look into the Future.- References.- 4. The Generation of Better Monoclonal Antibodies through Somatic Mutation.- 1. Introduction.- 2. Class and Subclass Switch Variants.- 3. Deletion Mutants.- 4. Antigen Binding Mutants.- 5. Conclusion.- References.- 5. Switching the Isotype of Monoclonal Antibodies.- 1. Introduction.- 2. Mouse Immunoglobulin isotypes.- 3. The Genetics of Immunoglobulin Isotype Expression.- 4. Spontaneous Isotype Switching in Myelomas and Hybridomas.- 5. Techniques of Switch Variant Selection.- 6. Kinetics of Isotype Switching.- 7. Effects of Mutagens on the Rate of Isotype Switching.- References.- 6. The Analysis of Structural Diversity in the Antibody Response.- 1. Introduction.- 2. RNA Sequencing.- 3. Analyzing Immunoglobulin Diversity by mRNA Sequencing.- 4. Protocol.- 5. Analyzing the Structural Diversity of the Antibody Response.- References.- 7. Expressions of Cloned Immunoglobulin Genes.- 1. Introduction.- 2. Mechanism of Immunoglobulin Gene Assembly.- 3. Assembly of Transfected Genes.- 4. Control of Immunoglobulin Gene Expression.- 5. Expression of Introduced Genes.- 6. Transgenic Mice.- 7. Summary.- References.- II. Monoclonal Antibodies in Biomedical Research: Principles and Applications.- 8. The Immunochemistry of Monoclonal Antibodies: Studies on One Immunologic Supergene (HLA) with the Products of Another.- 1. Introduction.- 2. Fragmentation of IgG to Give F(ab')2 and Fab.- 3. Fab/c: A Univalent Fragment with Effector Function.- 4. Isotype Switch Variants.- 5. Binding of Monoclonal Antibodies to Cell Surface Antigens.- 6. Hybrid Antibodies.- 7. Enhancing Effects of Monoclonal Antibodies in Solution.- 8. Quantitative Serologic Analysis of HLA-A, B Molecules.- 9. Epitope Mapping.- References.- 9. Purification of Membrane Glycoproteins with Monoclonal Antibody Affinity Columns.- 1. Introduction.- 2. Key Aspects in Monoclonal Antibody Affinity Chromatography.- 3. Purifications Based on Antigenic Determinants Stable to Denaturation.- References.- 10. Transferrin Receptor.- 1. Introduction.- 2. Structure of the Transferrin Receptor.- 3. Functional Aspects of the Transferrin Receptor.- 4. Gene Transfer and Molecular Cloning of the Human Transferrin Receptor.- 5. Concluding Remarks.- References.- 11. Functional and Structural Interrelationships among the Mac-1, LFA-1 Family of Leukocyte Adhesion Glycoproteins, and their Deficiency in a Novel Heritable Disease.- 1. Introduction.- 2. Probing Cell Surface Functions with Monoclonal Antibodies.- 3. Functional Properties of LFA-1.- 4. Functional Properties of Mac-1, a Molecule Related to LFA-1.- 5. Glycoprotein Family Interrelationships.- 6. Mac-1, LFA-1 Deficiency Disease.- References.- 12. Demonstration of Receptor Function of Membrane Proteins by Selection and Immobilization with Monoclonal Antibodies.- 1. Background.- 2. Demonstration of Specificity of Monoclonal Antibody-Immobilized Antigen for Particulate Ligand.- 3. Demonstration of Specificity of Monoclonal Antibody-Immobilized Antigen for Soluble Ligand.- 4. Summary.- References.- 13. Production of Rat × Mouse Hybridomas for the S.