Schisler jonathan (7 Ergebnisse)

Hardcover. Zustand: Good. No Jacket. First Edition. This could have light cosmetic flaws, but remains in good condition. No dust jacket included with this book. This copy is the First Edition of the published work. This copy is the First Printing of the published work. Secure packaging for safe delivery.…

Taschenbuch. Zustand: Neu. Neuware - A Tome of Poetry! Life, experiences, dreams, esoterica, past-lives. other people, love, feeling, a kangaroo rat, drama, squirrels, trees. metaphor and allegory. The historical, the planet, the Human Condition, the stupid. this book is full of feels and fun. Formats and styles are extremely eclectic. It's difficult to really describe it. The poetry is real. All of it sourced from 1 human life. (Mine). A lot of free-verse and haiku. Poetry is what bleeds from the soul. it's color and vibration. Observation, impression, feeling. Poetry does not have to obey a formula. And then it can. I would love for teachers to utilize my work in classrooms. I have 20+ years in education on the front lines myself, and postgraduate work in Secondary English. I would want aspiring authors or young people to see through my work, all of the different things poetry can be; chiefly, your authentic self. Your experiences. Inspirations. The book should be clean enough for classroom-use; I'm not big on cursing and I find creative ways around more intense expressions. Cover: A full-photo I took of a beautiful heritage maple that sadly no longer exists. But. now immortalized on a book of poetry! Title and Author are minimal, in gold, located on spine, so that the picture is unobstructed when the book is fully opened. Perfect for your coffee table. Or someone else's coffee table. because you probably don't have one. Title: More symbolic than literal. Although it comes from one of the most intense storms I've ever been rocked by. Digital Version: 341+ pages as Reflowable Text. (No page-breaks). Designed for Tech. Paperback: 341+ pages. Format as-intended. Full photo of tree. Gloss-cover. Hardcover: 341+ pages. Format as-intended. Full photo of tree. Gloss-cover. …

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. In English.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Fibroproliferative diseases are a broad spectrum of entities from organ-specific involvement (e.g., pulmonary, heart, liver, and kidney fibrosis) to multi-system diseases such as systemic sclerosis and sclerodermatous graft vs. host disease. These diseases also encompass pathophysiologies not readily recognizably related, such as macular degeneration and cancer metastasis. Fibroproliferative diseases are a leading cause of morbidity and mortality and can affect all tissues and organ systems. Remarkable progress in elucidating the pathogenesis of these common diseases with fibrotic components, including the critical roles of myofibroblasts and the molecular mechanisms driving the transcriptional activation involved in the induction of fibrosis. As the importance of these processes is realized in the long-term recovery and treatment of diseases, effective anti-fibrotic therapies targeting the underlying ongoing disease processes are lacking.The complexity of discovering and applying therapies to fibroproliferative disease may be due to the diversity of the systems the pathogenesis of disease itself involves. By nature, fibroproliferative diseases are interdisciplinary, involving multiple cell types (organ-specific epithelial cells), immune cells, endothelial cells, and fibroblasts. Bone marrow, cytokines, and organ-specific pathologies further speckle both the clinical and scientific disciplines in such a way that communication is often limited to the clinical or scientific tribes we live in, despite the greatest access to information known to man available today. Therefore, the primary focus of this text is to bring together authors from a diversity of both clinical, scientific, and therapeutic backgrounds for readers to more fully appreciate that fantastic platform that is available to build upon to lessen the isolation of the clinical and scientific disciplines. With advances in the discovery of pre-clinical therapeutic targets (at least 20+ to date) involving TGF-beta (and other cytokines), transcription factors, and downstream kinases, it's important to both recognize the broader impact and potential opportunities that exist even today.This book will serve as a state-of-the-art resource for physicians and translational medical researchers alike who are interested in the rapidly evolving field of fibroproliferative diseases. The book will provide new insight into the fundamental mechanisms of classic fibrotic pathophysiologic processes like myocardial infarction, idiopathic pulmonary fibrosis, chronic kidney disease, wound healing, and systemic sclerosis. It will also highlight the many new areas of therapeutic investigation currently underway. Lastly, we will touch upon newly emerging fields investigating the role of fibrosis in macular degeneration and cancer metastasis.The chapters will be written by established experts in their fields, including clinicians (cardiologists, cardiovascular surgeons, pathologists, and general practitioners) and translational biomedical researchers in a wide range of disciplines. However, the material will certainly have a broader audience including medical residents, fellows, and general practitioners as well as M.D. or Ph.D. post-doctoral research fellows. While comprehensive, we'll attempt to present the material in a manner that simplifies the complex pathophysiologic mechanisms that underlie common fibroproliferative diseases while making it appealing to a broad audience. …

Gebunden. Zustand: New. Develops the concept of the heart as both an endocrine organ and an endocrine target, exploring the endocrine function of the heart in both health and disease Explains how the levels of several cardiac hormones are changed in various cardi.

Hardcover. Zustand: Neu. Neu Neu - Neuware, Importqualität, auf Lager - Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart covers the traditional concepts of cardio-endocrinology, the role of the various hormone systems, both in health and disease, therapeutic implications, and other recent advances in the various fields represented. The book explores how cardiac hormones are changed in various cardiac pathologies and the recent success that has been uncovered in their therapeutic use. Additional focus is placed on how the heart responds both physiologically and pathophysiologically to a plethora of circulating hormones, reinforcing the importance of the heart as a target of numerous endocrine systems, such as the brain, renal, and adipose. Significant advances have come from basic, clinical, and translational research from a multiplicity of investigators with diverse backgrounds. The book features over 200 photomicrographs, diagrams of molecular relationships, and tables that complement and support the text. It is aimed at a wide audience, including graduate students and post-doctoral fellows in a wide array of biomedical departments and PhD programs (e.g. Pathology, Physiology, Genetics, Pharmacology, Molecular Biology, and Cell Biology) related to the endocrine and cardiovascular sciences curricula, as well as medical residents in pathology, laboratory medicine, internal medicine, and cardiology.…