Nikolaos labrou (32 Ergebnisse)
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume explores detailed methods and experimental protocols evaluating the effect of a compound or a mixture of compounds on the action of enzymes that are significant targets in pharmaceuticals. Consisting of three sections, the book delves int…o recent biocomputing and bioinformatics protocols, state-of-the art modern biophysical, electrophoretic, and chromatographic methods and high-throughput screening approaches, as well as detailed protocols and examples of the inhibition analysis and evaluation of selected enzymes. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Targeting Enzymes for Pharmaceutical Development: Methods and Protocols serves as a vital reference for academics and industry professionals working on expanding our understanding of the wide range of important enzyme targets.
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Taschenbuch. Zustand: Neu. Protein Downstream Processing | Design, Development and Application of High and Low-Resolution Methods | Nikolaos E. Labrou | Taschenbuch | xv | Englisch | 2016 | Humana | EAN 9781493960408 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 141…97 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
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Taschenbuch. Zustand: Neu. Therapeutic Enzymes: Function and Clinical Implications | Nikolaos Labrou | Taschenbuch | Advances in Experimental Medicine and Biology | viii | Englisch | 2020 | Springer | EAN 9789811377112 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]har…tmann[at]springer[dot]com | Anbieter: preigu.
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Taschenbuch. Zustand: Neu. Protein Downstream Processing | Design, Development, and Application of High and Low-Resolution Methods | Nikolaos E. Labrou | Taschenbuch | xv | Englisch | 2021 | Humana | EAN 9781071607770 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hart…mann[at]springer[dot]com | Anbieter: preigu.
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Zustand: New. Editor(s): Labrou, Nikolaos. Series: Methods in Molecular Biology. Num Pages: 570 pages, 59 black & white illustrations, 62 colour illustrations, 23 black & white tables, biograp. BIC Classification: PSBC. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 29. Weight in Grams: 1075. . 2016. Softcover r…eprint of the original 1st ed. 2014. Paperback. . . . . Books ship from the US and Ireland.
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This second edition volume expands on the previous edition with a discussion of the latest experimental and computational strategies used in the study, characterization, and targeting of enzymes with therapeutic potential. The chapters in the book are organ…ized into two parts: Part One presents detailed, reproducible protocols for enzyme characterization, inhibitor screening, and biochemical analysis. Part Two is dedicated to computational and in silico methodologies, reflecting the growing impact of computational biology in drug discovery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and authoritative, Targeting Enzymes for Pharmaceutical Development: Methods and Protocols, Second Edition is a valuable resource for academic and industrial scientists in medicinal chemistry, chemical biology, pharmaceutical biotechnology, structural biology, and computational drug discovery. This book is both a technical manual and conceptual guide for scientists engaged in enzyme-related drug discovery and development.
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Therapeutic enzymes exhibit fascinating features and opportunities, and represent a significant and promising subcategory of modern biopharmaceuticals for the treatment of several severe diseases. Research and drug developments efforts and the advanc…ements in biotechnology over the past twenty years have greatly assisted the introduction of efficient and safe enzyme-based therapies for a range of both rare and common disorders. The introduction and regulatory approval of twenty different recombinant enzymes has enabled effective enzyme-replacement therapy. This volume aims to overview these therapeutic enzymes, focusing in particular on more recently approved enzymes produced by recombinant DNA technology. This volume is composed of four sections. Section 1 provides an overview of the production process and biochemical characterization of therapeutic enzymes, while Section 2 focuses upon the engineering strategies and delivery methods of therapeutic enzymes. Section 3 highlights the clinical applications of approved therapeutic enzymes, including aspects on their structure, indications and mechanisms of action. Together with information on these mechanisms, safety and immunogenicity issues and various adverse events of the recombinant enzymes used for therapy are discussed. Section 4, provides discussion on the prospective and future developments of new therapeutic enzymes. This book is aimed at academics, researchers and students undertaking advanced undergraduate/postgraduate programs in the biopharmaceutical/biotechnology area who wish to gain a comprehensive understanding of enzyme-based therapeutic molecules.
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This second edition volume expands on the previous edition with updated research and techniques to help laboratory workers design and implement a successful purification strategy, emphasize critical aspects on practical problems, and answers question…s encountered at the lab bench. The chapters in this book are divided into five parts: Part One discusses an overview of screening and design of purification strategies and covers initial aspects on high-throughput screening, methods development, and media selection; Parts Two and Three explore low- and high-resolution methods, with emphasis on affinity chromatography; Part Four describes analytical techniques of purified proteins; and Part Five presents selected examples and case studies to discuss the aforementioned. Written in the highly successfulMethods in Molecular Biologyseries format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and comprehensive,Protein Downstream Processing: Design, Development, and Application of High and Low-Resolution Methods, Second Editionis an ideal source of information to advanced students, junior researchers, and scientists involved in health sciences, cellular and molecular biology, biochemistry, biotechnology, and other related areas in both academia and industry.
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume explores detailed methods and experimental protocols evaluating the effect of a compound or a mixture of compounds on the action of enzymes that are significant targets in pharmaceuticals. Consisting of three sections, the book delves into recen…t biocomputing and bioinformatics protocols, state-of-the art modern biophysical, electrophoretic, and chromatographic methods and high-throughput screening approaches, as well as detailed protocols and examples of the inhibition analysis and evaluation of selected enzymes. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Targeting Enzymes for Pharmaceutical Development: Methods and Protocols serves as a vital reference for academics and industry professionals working on expanding our understanding of the wide range of important enzyme targets.
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Sprache: Englisch
Verlag: Springer Nature Singapore, Springer Nature Singapore, 2019
Serie: Buch 443 von 544 - Advances in Experimental Medicine and Biology
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Therapeutic enzymes exhibit fascinating features and opportunities, and represent a significant and promising subcategory of modern biopharmaceuticals for the treatment of several severe diseases. Research and drug developments efforts and the advancements…in biotechnology over the past twenty years have greatly assisted the introduction of efficient and safe enzyme-based therapies for a range of both rare and common disorders. The introduction and regulatory approval of twenty different recombinant enzymes has enabled effective enzyme-replacement therapy. This volume aims to overview these therapeutic enzymes, focusing in particular on more recently approved enzymes produced by recombinant DNA technology. This volume is composed of four sections. Section 1 provides an overview of the production process and biochemical characterization of therapeutic enzymes, while Section 2 focuses upon the engineering strategies and delivery methods of therapeutic enzymes. Section 3 highlights the clinical applications of approved therapeutic enzymes, including aspects on their structure, indications and mechanisms of action. Together with information on these mechanisms, safety and immunogenicity issues and various adverse events of the recombinant enzymes used for therapy are discussed. Section 4, provides discussion on the prospective and future developments of new therapeutic enzymes. This book is aimed at academics, researchers and students undertaking advanced undergraduate/postgraduate programs in the biopharmaceutical/biotechnology area who wish to gain a comprehensive understanding of enzyme-based therapeutic molecules.
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Zustand: New. Editor(s): Labrou, Nikolaos; Flemetakis, Emmanouil. Num Pages: 394 pages, illustrations. BIC Classification: PSBC. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly. Dimension: 264 x 182 x 25. Weight in Grams: 846. . 2013. 1st Edition. Hardcover. . . . . Books ship from the US and Ire…land.
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Zustand: New. Editor(s): Labrou, Nikolaos. Series: Methods in Molecular Biology. Num Pages: 570 pages, 59 black & white illustrations, 62 colour illustrations, 23 black & white tables, biograp. BIC Classification: PSBC; PSD. Category: (P) Professional & Vocational. Dimension: 259 x 183 x 34. Weight in Grams: 1202. . 2014. 2014th… Edition. hardcover. . . . . Books ship from the US and Ireland.
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This second edition volume expands on the previous edition with updated research and techniques to help laboratory workers design and implement a successful purification strategy, emphasize critical aspects on practical problems, and answers questions encou…ntered at the lab bench. The chapters in this book are divided into five parts: Part One discusses an overview of screening and design of purification strategies and covers initial aspects on high-throughput screening, methods development, and media selection; Parts Two and Three explore low- and high-resolution methods, with emphasis on affinity chromatography; Part Four describes analytical techniques of purified proteins; and Part Five presents selected examples and case studies to discuss the aforementioned. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and comprehensive, Protein Downstream Processing: Design, Development, and Application of High and Low-Resolution Methods, Second Edition is an ideal source of information to advanced students, junior researchers, and scientists involved in health sciences, cellular and molecular biology, biochemistry, biotechnology, and other related areas in both academia and industry.
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