michael adu (11 Ergebnisse)

Zustand: Good. Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, but in good overall condition. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions.

Zustand: Good. 1st Edition. Ships from the UK. Used book that is in clean, average condition without any missing pages.

Zustand: Good. Used book that is in clean, average condition without any missing pages.

Zustand: Very Good. Former library book; may include library markings. Used book that is in excellent condition. May show signs of wear or have minor defects.

Zustand: Good. Used book that is in clean, average condition without any missing pages.

Taschenbuch. Zustand: Neu. Cis-regulatory elements underlying Prdm15 gene during brain development | Michael Adu | Taschenbuch | Englisch | 2022 | GRIN Verlag | EAN 9783346579591 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Bachelor Thesis from the year 2018 in the subject Biology - Genetics / Gene Technology, grade: 2.5, University of Cape Coast (Department of biochemistry - University of Cape Coast), course: Biochemistry, language: English, abstract: The interaction between transcriptional factors and cis-regulatory DNA element has given rise to the diversity in the expression of eukaryotic gene. Prdm15 gene is known to be expressed in the brain throughout development of mouse and zebrafish however; there are no known enhancer(s) for this gene in the brain. The aim of this study was to identify brain specific enhancer(s) for the gene Prdm15 during brain development. The VISTA enhancer browser and Encyclopedia of DNA Elements (ENCODE) data were used in this study to determine our candidate brain enhancer. The VISTA enhancer browser was used to quest for cis-regulatory element(s) in the environs of Prdm15 by comparative genomics and only one candidate enhancer we designated Prdm15 control element 1(PCE1) was identified downstream of the gene. PCE1 was found to be conserved in organisms such as chicken, zebrafish, rhesus, chimp, dog and cow. To ascertain if PCE1 is a brain enhancer, we delineated PCE1 using brain-specific enhancer chromatin modification signatures H3K4me1 and H3K27ac in the ENCODE data and they showed enrichment for PCE1. In conclusion, our data set revealed that only one brain candidate enhancer (PCE1) exist for Prdm15 and that this brain enhancer for Prdm15 will help in identifying important upstream specific transcription factors of PrdmI5 during brain development.

Taschenbuch. Zustand: Neu. Neuware -Bachelor Thesis from the year 2018 in the subject Biology - Genetics / Gene Technology, grade: 2.5, University of Cape Coast (Department of biochemistry - University of Cape Coast), course: Biochemistry, language: English, abstract: The interaction between transcriptional factors and cis-regulatory DNA element has given rise to the diversity in the expression of eukaryotic gene. Prdm15 gene is known to be expressed in the brain throughout development of mouse and zebrafish however; there are no known enhancer(s) for this gene in the brain. The aim of this study was to identify brain specific enhancer(s) for the gene Prdm15 during brain development. The VISTA enhancer browser and Encyclopedia of DNA Elements (ENCODE) data were used in this study to determine our candidate brain enhancer. The VISTA enhancer browser was used to quest for cis-regulatory element(s) in the environs of Prdm15 by comparative genomics and only one candidate enhancer we designated Prdm15 control element 1(PCE1) was identified downstream of the gene. PCE1 was found to be conserved in organisms such as chicken, zebrafish, rhesus, chimp, dog and cow. To ascertain if PCE1 is a brain enhancer, we delineated PCE1 using brain-specific enhancer chromatin modification signatures H3K4me1 and H3K27ac in the ENCODE data and they showed enrichment for PCE1. In conclusion, our data set revealed that only one brain candidate enhancer (PCE1) exist for Prdm15 and that this brain enhancer for Prdm15 will help in identifying important upstream specific transcription factors of PrdmI5 during brain development. 44 pp. Englisch.

1st ed. 'Damaged' stamp on title page - corners of front board slightly bumped; front cover scratched; internally as-new. Used - Very Good. VG hardback in laminated boards Used - Very Good. VG hardback in laminated boards.

Gebundene Ausgabe. Zustand: Sehr gut. Gebraucht - Sehr gut Mängelexemplar mit leichten Lagerspuren, Sofortversand - Rheumatology and the Kidney offers views on the causes and treatment of kidney diseases that complicate various rheumatologic diseases. The book includes pathogenesis, clinical features and treatment of diseases providing a source of clinical advice for day to day practice.<.

Paperback. Zustand: Brand New. 2nd edition. 466 pages. 9.00x6.00x1.00 inches. In Stock.