mansour mahmoud ahmed (5 Ergebnisse)

Zustand: New. In.

Zustand: New. In.

Buch. Zustand: Neu. Neuware -Oxidoreductase enzymes are a group of enzymes that catalyzes the transfer of electrons from one molecule, the reductant, also called the electron donor, to another, the oxidant, also called the electron acceptor. Oxidoreductase enzymes utilize NADP+ or NAD+ as cofactors. Oxidoreductase enzymes include the following: oxidase, dehydrogenase, peroxidase, hydroxylase, oxygenase, and reductase. Most oxidoreductase enzymes are dehydrogenases. However, reductases are also common. The accepted nomenclature for dehydrogenases is ¿donor dehydrogenase¿, where the donor is the oxidized substrate. Metabolic abnormalities disorders resulting from a deficiency (quantitative and qualitative) or from over-activity of oxidoreductase, which may contribute to the decreased normal performance of life, are becoming common. This book covers the potential applications of oxidoreductases on the growth of oxidoreductase-based diagnostic tests and better biosensors in the design of inventive systems for crucial co-enzyme generations and in the synthesis of polymers and organic substrates. The book describes the role of oxidoreductase as essential in medical drug formation. It can be employed to produce a huge amount of compounds that act as medical mediators like Cephalosporin (beta lactam antibiotic). Furthermore, the idea of how to use different enzymes as targets for medical treatment in different types of cancers is also described in this book.Books on Demand GmbH, Überseering 33, 22297 Hamburg 180 pp. Englisch.

Buch. Zustand: Neu. Neuware -Lipid peroxidation is the major molecular mechanism that induces oxidative damage to cell structures and is also involved in the toxicity process that leads to cell death.Lipid peroxidation is a chain reaction initiated by the hydrogen abstraction or addition of an oxygen radical, resulting in the oxidative damage of polyunsaturated fatty acids (PUFA). PUFAs are more sensitive than saturated fatty acids because of the presence of a double bond adjacent to a methylene group that makes the methylene C-H bond weaker and therefore the hydrogen is more susceptible to abstraction. This leaves an unpaired electron on the carbon, forming a carbon-centered radical, which is stabilized by a molecular rearrangement of the double bonds to form a conjugated diene, which then combines with oxygen to form a peroxy-radical.In pathological situations the reactive oxygen and nitrogen species are generated at higher than normal rates, and as a consequence, lipid peroxidation occurs with deficiency of endogenous antioxidants as alpha-tocopherol deficiency or reduced glutathione. In addition to containing high concentrations of PUFAs and transition metals, biological membranes of cells and organelles are constantly being subjected to various types of damage.This book presents systematic and comprehensive reviews on free radicals and their involvement in lipid peroxidation with special emphasis on their important role in different diseases.Books on Demand GmbH, Überseering 33, 22297 Hamburg 128 pp. Englisch.

Buch. Zustand: Neu. Neuware -In the dynamic world of cellular biology, the intricate dance of life and death plays out through the lens of cytotoxicity. Delve deep into cellular responses¿ mysteries, where threats and defenses wage a microscopic war, influencing the broader landscape of health and disease. This authoritative volume on cytotoxicity encapsulates the breadth and depth of current knowledge, illuminating pathways that have been meticulously charted and those yet to be discovered. Each chapter, penned by experts in the field, unveils the molecular intricacies, external triggers, and translational potential of understanding cellular damage. Key Highlights: ¿Comprehensive explorations of molecular mechanisms ¿Cutting-edge methodologies in cytotoxic research ¿Insight into the profound implications for drug development and disease therapeutics Whether you are a seasoned researcher, an aspiring scientist, or an avid learner, this book promises to challenge, enlighten, and inspire. As the boundary between known territories and uncharted frontiers blurs, Cytotoxicity - Understanding Cellular Damage and Response is your definitive guide to a world where cellular responses hold the keys to groundbreaking discoveries. This book is an indispensable resource for anyone eager to navigate the complexities of cell damage and defense. Join us on a journey into the cellular realm, where every page turns a new chapter in understanding, innovation, and hope.Books on Demand GmbH, Überseering 33, 22297 Hamburg 244 pp. Englisch.