Maccorquodale (17 Ergebnisse)

Zustand: Good. Pages intact with minimal writing/highlighting. The binding may be loose and creased. Dust jackets/supplements are not included. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.

Hardcover. Zustand: Very Good. Dust Jacket Included. 277 pages, a very good hardback in a very good dust-jacket [029907840X].

8° gebundene Ausgabe. Zustand: Sehr gut. XIV, 273 S. : graph. Darst. ; 24 cm Ausgetragenes Bibliotheksexemplar , Preise inkl. Mwst. B15-04-04O Sprache: Englisch Gewicht in Gramm: 584.

Zustand: Good. Good condition. Good dust jacket. A copy that has been read but remains intact. May contain markings such as bookplates, stamps, limited notes and highlighting, or a few light stains.

hardcover. Zustand: Good. Very Good text and cover. Dust jacket has a few edge tears/nicks and small chips, DJ is folded off center, likely printed/cut off-center, typical to this book. US orders shipped via US Mail. International orders shipped via DHL. Additional postage may be required on oversize books and sets. NO prison orders.…

Hardcover. Zustand: Good. No Jacket. 1st ed. xv+379; fr.pastedown has sig., ex-libris stamp and library donation label of same person, t.p. has impressed colourless round stamp of same, underlining + occ. marginal marking pp.12-17 (Clark Hull chapter by Koch), more seriously however verso last page, endpaper and rear pastedown are covered with pencilled notes and also have suffered some kind of adhesion problem as leaves have several holes and pastedown is wrinkled - if it is indeed the pastedown as it appears to be a leaf overlaying the pastedown. Green cloth covers clean and generally sound but spine faded and end-rubbed. Clearly a reference/working copy only of this important set of essays on Clark Hull, Tolman, Skinner, Kurt Lewin and Guthrie, with nearly half being devoted to Koch's merciless demolition of Hull's entire system (he died 2 years before publication and my suspicion, on no evidence at all, is that publication was delayed to spare his feelings, as the book emerged from a group effort in summer 1950). Essential reading for any serious historian of mid-20th century US behaviorism. …

pamphlet. Zustand: very good. First. Illustrated. 14 pages (pp. 435-448) FROM: Journal of Biological Chemistry, Vol. 115, 1936. Slim 8vo, modern paper wrappers. Baltimore, 1936. First edition. Very good. Isolation of Oestradiol. With S.A. Thayer and E.A. Doisy. GM 1202.

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. In.

Paperback. Zustand: Brand New. 84 pages. 8.66x5.91x0.19 inches. In Stock.

Paperback. Zustand: Brand New. reprint edition. 287 pages. 9.30x6.15x0.65 inches. In Stock.

Zustand: Used.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Recent political developments imply a much larger part of our economy will be devoted to civilian enterprises and a much smaller part to military work than in the recent past. This book examines the impact on the technical community, particularly engineers, of the conversion of defense-related industries to civilian-oriented activities. Currently about one third of all engineers work on military projects, and four fifths of all federal research and development is defense-related. The essays in this volume are by academic researchers (in disciplines ranging from psychology and philosophy to economics and engineering), engineers and managers from companies that work on military projects, and representatives of some of the professional societies of engineers. They address the questions: What will be the impact on the technical community of the economic conversion What effect will the technical community have on the conversion What actions can one take to minimize the destructive and maximize the constructive effects of the conversion What are the implications for engineering education, professional work, and public policy.…

Zustand: Used.

Taschenbuch. Zustand: Neu. Shostakovich | The Moral Conscience of Russia | Elizabeth MacCorquodale | Taschenbuch | 84 S. | Englisch | 2016 | AV Akademikerverlag | EAN 9783330511576 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu.…

Zustand: Hervorragend. Zustand: Hervorragend | Seiten: 350 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.

First Edition. Doisy received the Nobel Prize in Physiology or Medicine in 1943 for determining the chemical nature of vitamin K, the fat-soluble compound whose absence from the diet produces uncontrolled hemorrhage by impairing the blood's ability to clot. The vitamin had been identified as a distinct nutritional factor by Henrik Dam in 1935, but its chemical identity remained unknown until Doisy's laboratory at Saint Louis University isolated, characterized, and synthesized both of its naturally occurring forms. The four papers gathered here trace that achievement in compact form: two brief 1939 communications establishing the antihemorrhagic activity of synthetic quinones and proposing a practical standard for their assay; a 1940 note summarizing the structural determinations of vitamins K and K and reporting the preparation of water-soluble derivatives suitable for clinical use; and a major 1941 review consolidating the chemistry, biological testing, and structural elucidation of the entire vitamin K group. Together they document not merely the identification of a vitamin, but the rapid conversion of a nutritional observation into a coherent biochemical program linking isolation, synthesis, standardization, and therapeutic application. Vitamin K is today administered to virtually every newborn in the developed world to prevent fatal bleeding, and remains essential to the management of clotting disorders and anticoagulant therapy. [Thayer, S. A., L. C. Cheney, S. B. Binkley, D. W. MacCorquodale, and E. A. Doisy]. "Vitamin K Activity of Some Quinones; reprinted from the Journal of the American Chemical Society, Vol. 61, p. 1932." Easton, PA: American Chemical Society, 1939. Offprint, single leaf, trimmed 8vo (186 × 199mm). Trimmed at the bottom, old tape offsetting to the margin, else very good. A brief communication reporting the vitamin K activity of an extensive series of quinone derivatives assayed against natural vitamins K and K as standards. Written in direct response to Almquist and Klose's claim that phthiocol was the simplest active member of the antihemorrhagic series, the paper demonstrates that all derivatives of 1,4-naphthoquinone - with the exception of 2-allyl-1,4-naphthoquinone - show measurable vitamin K activity, with 2-methyl-1,4-naphthoquinone the most potent at 10 units per milligram, though markedly less active than the natural vitamins. The activity of two dihydro-1,4-naphthoquinone diacetates is attributed to gastrointestinal hydrolysis, and the paper cross-references the concurrent structural determination of vitamin K published in the same journal volume. [Thayer, S. A., S. B. Binkley, D. W. MacCorquodale, E. A. Doisy, A. D. Emmett, Raymond A. Brown, and Orson D. Bird]. "Vitamin K Potencies of Synthetic Compounds; reprinted from the Journal of the American Chemical Society, Vol. 61, p. 2563, 1939." Easton, PA: American Chemical Society, 1939. Offprint, single leaf, trimmed 8vo (192 × 200mm). Trimmed at the bottom, old tape offsetting to the margin, else very good. A follow-up communication conducted in collaboration with the Research Laboratories of Parke, Davis and Company, supplementing the quinone activity survey of the preceding paper. The principal finding is that 1,4-dihydroxy-2-methylnaphthalene, readily prepared by reduction of 2-methyl-1,4-naphthoquinone, possesses a potency of approximately 1,000 Thayer-Doisy units per milligram and has the clinical advantage of solubility in dilute alkali, making it suitable for intravenous administration in patients unable to absorb oral preparations. The paper concludes with the proposal that 2-methyl-1,4-naphthoquinone be adopted as a universal assay standard, defined as the specific activity of one microgram of the pure compound in League of Nations committee units - a standardization recommendation with immediate practical significance for the clinical deployment of vitamin K therapy. [Doisy, E. A., S. B. Binkley, S. A. Thayer, E. W. McKee, and D. Richert]. "Antihemorrhagic Compounds; reprinted from Science, Vol. 91, No. 2366, p. 421, May 3, 1940." Washington, D.C.: American Association for the Advancement of Science, 1940. Offprint, single leaf, 8vo (230 × 153mm). Soft creases, else fine. A brief communication presented before the National Academy of Sciences, summarizing the structural program following the isolation of both natural antihemorrhagic compounds. The structure of vitamin K was deduced from degradation experiments and confirmed by synthesis; vitamin K , while sharing the 2-methyl-1,4-naphthoquinone core, bears a thirty-carbon hydrocarbon substituent at the 3-position in place of the phytyl chain of K . The water insolubility of both natural compounds limiting their suitability for parenteral use, the authors report the preparation of several water-soluble synthetic derivatives and their intravenous administration to vitamin K-deficient chicks, with activity assessed by restoration of prothrombin time to normal. [Doisy, E. A., S. B. Binkley, and S. A. Thayer]. "Vitamin K; reprinted from Chemical Reviews, Vol. 28, No. 3, pp. 477-517, 1941." Washington, D.C.: American Chemical Society, 1941. Offprint, 8vo (254 × 175mm), pp. 41, [1]. Printed wrappers, staple-bound, rubbing, toning, and light soiling, else very good. A comprehensive review providing an authoritative account of the vitamin K field at the point of its maturity. The paper moves systematically from Dam's original identification of an unknown fat-soluble antihemorrhagic factor in 1935 through the isolation, structural determination, and synthesis of vitamins K and K , before turning to a detailed structure-activity survey of synthetic quinone derivatives. The isolation sections describe the fractionation of alfalfa and putrefied fish meal that yielded K and K respectively; the structural sections document the deduction of the shared 2-methyl-1,4-naphthoquinone core and the characterization of the differing substituents at the 3-position; and an extensive.…