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hardcover. Zustand: Fine.

Taschenbuch. Zustand: Neu. Antimalarial Natural Products | A. Douglas Kinghorn (u. a.) | Taschenbuch | Progress in the Chemistry of Organic Natural Products | ix | Englisch | 2023 | Springer | EAN 9783030898755 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.…

Hardcover. Zustand: Brand New. 250 pages. 9.26x6.11x0.79 inches. In Stock.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine's biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine's structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type. Although the search for new antimalarial natural products from Nature's combinatorial library is challenging, it is very likely to yield new antimalarial drugs. This book thus ends byidentifying ten natural products with development potential as clinical antimalarial agents.…

Zustand: As New. Unread book in perfect condition.

Paperback. Zustand: Brand New. 115 pages. 9.25x6.10x0.35 inches. In Stock.

Zustand: New.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine's biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine's structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type. Although the search for new antimalarial natural products from Nature's combinatorial library is challenging, it is very likely to yield new antimalarial drugs. This book thus ends byidentifying ten natural products with development potential as clinical antimalarial agents. …

Hardcover. Zustand: Brand New. 350 pages. 9.25x6.10x8.90 inches. In Stock.

Taschenbuch. Zustand: Neu. Progress in the Chemistry of Organic Natural Products 118 | A. Douglas Kinghorn (u. a.) | Taschenbuch | Progress in the Chemistry of Organic Natural Products | v | Englisch | 2023 | Springer | EAN 9783030920326 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

Taschenbuch. Zustand: Neu. Modern Photocatalytic Strategies in Natural Product Synthesis | A. Douglas Kinghorn (u. a.) | Taschenbuch | Progress in the Chemistry of Organic Natural Products | ix | Englisch | 2024 | Springer | EAN 9783031117855 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.…

Zustand: New. This volume presents three chapters discussing a range of topics. Chapter 1 deals with the development of efficient methods for compound dereplication that have been critical in the re-emergence of research on natural products as a source of new drug lea.

Zustand: New. In English.

Taschenbuch. Zustand: Neu. Naturally Occurring Organohalogen Compounds | A. Douglas Kinghorn (u. a.) | Taschenbuch | Progress in the Chemistry of Organic Natural Products | vii | Englisch | 2024 | Springer | EAN 9783031266317 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

Taschenbuch. Zustand: Neu. Biologically Active Compounds of Malaysian Medicinal and Aromatic Plants | A. Douglas Kinghorn (u. a.) | Taschenbuch | Progress in the Chemistry of Organic Natural Products | vii | Englisch | 2026 | Springer | EAN 9783031863806 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book presents recent reports of total syntheses involving a photocatalytic reaction as a key step in the methodology.Modern photocatalysis has proven its generality for the development and functionalization of native functionalities. To date, the field has found broad applications in diverse research areas, including the total synthesis of natural products. Among the selected examples presented in this book, it highlights how the photocatalytic process proceeds in a highly chemo-, regio-, and stereoselective manner, thereby allowing the rapid access to structurally complex architectures under light-driven conditions.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume consists of four chapters that cover a structurally diverse range of naturally occurring compounds. Chapter 1 delves into the chemistry of pyrogallols and their oxidized products, the hydroxy-o-quinones, including their role in cycloaddition reactions in the chemical synthesis of several fungal metabolites. Chapter 2 provides an in-depth description of the constituents of agarwood essential oil and smoke samples that are used in the perfumery industry, with an emphasis on the sesquiterpenoid and chromones constituents so far known. Chapter 3 discusses the defensive chemical ecology of two North American newt species that both produce tetrodotoxin, a well-known neurotoxin that causes paralysis and death in metazoans by disrupting electrical signals in the nerves and muscles. Chapter 4 discusses the limonoids and triterpenoids from the genus Walsura of the plant family Meliaceae, of whicha number ofspecies are utilized in several southeastern Asian countries in systems of folk medicine. …

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book presents recent reports of total syntheses involving a photocatalytic reaction as a key step in the methodology.Modern photocatalysis has proven its generality for the development and functionalization of native functionalities. To date, the field has found broad applications in diverse research areas, including the total synthesis of natural products. Among the selected examples presented in this book, it highlights how the photocatalytic process proceeds in a highly chemo-, regio-, and stereoselective manner, thereby allowing the rapid access to structurally complex architectures under light-driven conditions.…

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book, ''Phytochemicals of Pteridophytes: Occurrence, Structures, and Biological Activity'', explores the chemical constituents of pteridophytes (lycophytes and ferns), emphasizing their occurrence, structures, and biological functions. It covers a wide range of phytochemicals, including aromatic compounds (e.g., acylphloroglucinols, flavonoids, lignans, selaginellins) and isoprenoids (e.g., monoterpenoids, norisoprenoids, sesquiterpenoids, diterpenoids, and steroids). The book examines the distribution of these compounds across various pteridophyte genera and species, highlights their structural diversity, and outlines their pharmacological properties. It also compares the phytochemical profiles of pteridophytes with those of algae and bryophytes.…

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book describes a unique class of secondary metabolites, the mono- and dimeric-naphthylisoquinoline alkaloids. They exclusively occur in lianas of the palaeotropical Ancistrocladaceae and Dioncophyllaceae plant families. Their unprecedented structures include stereogenic centers and rotationally hindered, and therefore stereogenic, axes. Extended recent investigations on six Ancistrocladus species from Asia, as reported in this contribution, shed light on their fascinating phytochemical productivity, with over 100 intriguing natural products. This high chemodiversity arises from a similarly unique biosynthesis from acetate-malonate units, following a novel polyketidic pathway to plant-derived isoquinoline alkaloids. Some of the compounds show most promising anti-parasitic activities. Additionally, strategies for the regio- and stereoselective total synthesis of the alkaloids, including the directed construction of the chiral axis, are also presented. …

Zustand: Hervorragend. Zustand: Hervorragend | Seiten: 348 | Sprache: Englisch | Produktart: Bücher | This book describes a unique class of secondary metabolites, the mono- and dimeric-naphthylisoquinoline alkaloids. They exclusively occur in lianas of the palaeotropical Ancistrocladaceae and Dioncophyllaceae plant families. Their unprecedented structures include stereogenic centers and rotationally hindered, and therefore stereogenic, axes. Extended recent investigations on six Ancistrocladus species from Asia, as reported in this contribution, shed light on their fascinating phytochemical productivity, with over 100 intriguing natural products. This high chemodiversity arises from a similarly unique biosynthesis from acetate-malonate units, following a novel polyketidic pathway to plant-derived isoquinoline alkaloids. Some of the compounds show most promising anti-parasitic activities. Additionally, strategies for the regio- and stereoselective total synthesis of the alkaloids, including the directed construction of the chiral axis, are also presented.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The book reviews the natural product chemistry of Australian rainforest plants, with a particular focus on their fascinating phylogenetic relationships. It discusses the unique flora of Australia, which is of Gondwanan origin, and how this has led to a diverse range of natural products. The text explores the chemical constituents of various plant groups, including those of gymnosperms, basal angiosperms, magnoliids, monocots, and eudicots, with an emphasis on the Australian rainforest species. Key points covered include the historical context of Australian flora, its high level of endemism, and the impact of past climatic changes on rainforest distribution. The book also details the specific phytochemicals found in these plants (about 2,400), such as alkaloids, lignans, and terpenoids, and their biological activities. Overall, this comprehensive volume highlights the importance of Australian rainforests as a rich source of unique natural products and emphasizes the need for further research in this area, in particular given that only approximately 10% of these rainforest species have been investigated so far.…

Taschenbuch. Zustand: Neu. Neurotrophic Natural Products | A. Douglas Kinghorn (u. a.) | Taschenbuch | Progress in the Chemistry of Organic Natural Products | ix | Englisch | 2025 | Springer | EAN 9783031424243 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume explores the biologically active compounds found in 21 high-value medicinal and aromatic plant species native to Malaysia, emphasizing their phytochemical diversity and biological activities. Several of these plants, including Eurycoma longifolia, Andrographis paniculata, Morinda citrifolia, Centella asiatica, and Moringa pleifera, have been prioritized as high-priority herbal products under Malaysia's National Key Economic Area in the Eleventh Malaysia Plan. Their importance transcends traditional herbal medicine, as they are increasingly recognized for their potential contributions to the national economy and modern healthcare. The volume describes the pharmacological properties of these plants, highlighting their anti-inflammatory, antioxidant, antimicrobial, and cytotoxic activities. It also encompasses aromatic plants like Clinacanthus nutans, Cananga odorata, Citrus hystrix, and Polygonum minus, focusing on their bioactive compounds and potential therapeutic and industrial uses.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume presents three chapters discussing a range of topics. Chapter 1 deals with the development of efficient methods for compound dereplication that have been critical in the re-emergence of research on natural products as a source of new drug leads. It describes the main methods of dereplication, which rely on the combined use of large natural product databases and spectral libraries, alongside the information obtained from chromatographic, UV-Vis, MS, and NMR spectroscopic analyses of the samples of interest. Chapter 2 describes 989 plant natural products and their ecological functions in plant-herbivore, plant-microorganism, and plant-plant interactions. These compounds include alkaloids, phenols, terpenoids, and other structural types. The information presented should provide the basis for in-depth research on these plant natural products and their natural functions, and also for their further development and utilization. Chapter 3 focuses on lichens, with each constituting a symbiotic association composed of a primary mycobiont and one or more photobionts living mutualistically. Covered are lichens and their bionts, taxonomic identification, and their chemical constituents as exemplified by what is found in lichen biomes, especially those endemic to North America. Extraction and isolation procedures, as well as updates on dereplication methods using mass spectrometric GNPS and NMR spectroscopic spin network fingerprint procedures, and marker-based techniques to identify lichens are discussed. The isolation and structure elucidation of secondary metabolites of an endolichenic Penicillium species that produces bioactive compounds is described in detail.…

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The book reviews the natural product chemistry of Australian rainforest plants, with a particular focus on their fascinating phylogenetic relationships. It discusses the unique flora of Australia, which is of Gondwanan origin, and how this has led to a diverse range of natural products. The text explores the chemical constituents of various plant groups, including those of gymnosperms, basal angiosperms, magnoliids, monocots, and eudicots, with an emphasis on the Australian rainforest species. Key points covered include the historical context of Australian flora, its high level of endemism, and the impact of past climatic changes on rainforest distribution. The book also details the specific phytochemicals found in these plants (about 2,400), such as alkaloids, lignans, and terpenoids, and their biological activities. Overall, this comprehensive volume highlights the importance of Australian rainforests as a rich source of unique natural products and emphasizes the need for further research in this area, in particular given that only approximately 10% of these rainforest species have been investigated so far. …

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume explores the biologically active compounds found in 21 high-value medicinal and aromatic plant species native to Malaysia, emphasizing their phytochemical diversity and biological activities. Several of these plants, including Eurycoma longifolia, Andrographis paniculata, Morinda citrifolia, Centella asiatica, and Moringa pleifera, have been prioritized as high-priority herbal products under Malaysia's National Key Economic Area in the Eleventh Malaysia Plan. Their importance transcends traditional herbal medicine, as they are increasingly recognized for their potential contributions to the national economy and modern healthcare. The volume describes the pharmacological properties of these plants, highlighting their anti-inflammatory, antioxidant, antimicrobial, and cytotoxic activities. It also encompasses aromatic plants like Clinacanthus nutans, Cananga odorata, Citrus hystrix, and Polygonum minus, focusing on their bioactive compounds and potential therapeutic and industrial uses.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The present volume is the third in a trilogy that documents naturally occurring organohalogen compounds, bringing the total number - from fewer than 25 in 1968 - to approximately 8,000 compounds to date. Nearly all of these natural products contain chlorine or bromine, with a few containing iodine and, fewer still, fluorine. Produced by ubiquitous marine (algae, sponges, corals, bryozoa, nudibranchs, fungi, bacteria) and terrestrial organisms (plants, fungi, bacteria, insects, higher animals) and universal abiotic processes (volcanos, forest fires, geothermal events), organohalogens pervade the global ecosystem. Newly identified extraterrestrial sources are also documented. In addition to chemical structures, biological activity, biohalogenation, biodegradation, natural function, and future outlook are presented.…

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The present volume is the third in a trilogy that documents naturally occurring organohalogen compounds, bringing the total number - from fewer than 25 in 1968 - to approximately 8,000 compounds to date. Nearly all of these natural products contain chlorine or bromine, with a few containing iodine and, fewer still, fluorine. Produced by ubiquitous marine (algae, sponges, corals, bryozoa, nudibranchs, fungi, bacteria) and terrestrial organisms (plants, fungi, bacteria, insects, higher animals) and universal abiotic processes (volcanos, forest fires, geothermal events), organohalogens pervade the global ecosystem. Newly identified extraterrestrial sources are also documented. In addition to chemical structures, biological activity, biohalogenation, biodegradation, natural function, and future outlook are presented.…

Zustand: New. Provides comprehensive and up-to-date reviews on the topicWritten by recognized authorities in the fieldIs part of a well-known seriesThis book deals with neurotrophins (NGF, BDNF, NT3, NT4), which can decrease cel.