lecea luis (16 Ergebnisse)

Zustand: New. pp. 468 Illus.

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. In.

Zustand: New. In.

Paperback. Zustand: Brand New. 465 pages. 9.25x6.10x1.10 inches. In Stock.

Zustand: New. Editor(s): Lecea, Luis de (The Scripps Research Institute La Jolla); Sutcliffe, J. Gregor (The Scripps Research Institute La Jolla). Num Pages: 465 pages, 11 black & white tables, biography. BIC Classification: MJG; MJN; PSAN. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 24. Weight in Grams: 712. . 2014. Paperback. . . . . Books ship from the US and Ireland.

Hardcover. Zustand: Brand New. 1st edition. 439 pages. 9.25x6.25x1.25 inches. In Stock.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The first report that rapid eye movements occur in sleep in humans was published in 1953. The research journey from this point to the realization that sleep consists of two entirely independent states of being (eventually labeled REM sleep and non-REM sleep) was convoluted, but by 1960 the fundamental duality of sleep was well established including the description of REM sleep in cats associated with 'wide awake' EEG patterns and EMG suppression. The first report linking REM sleep to a pathology occurred in 1961 and a clear association of sleep onset REM periods, cataplexy, hypnagogic hallucinations and sleep paralysis was fully established by 1966. When a naïve individual happens to observe a full-blown cataplexy attack, it is both dramatic and unnerving. Usually the observer assumes that the loss of muscle tone represents syncope or seizure. In order to educate health professionals and the general public, Christian Guilleminault and I made movies of full-blown cataplectic episodes (not an easy task). We showed these movies of cataplexy attacks to a number of professional audiences, and were eventually rewarded with the report of a similar abrupt loss of muscle tone in a dog. We were able to bring the dog to Stanford University and with this as the trigger, we were able to develop the Stanford Canine Narcolepsy Colony. Breeding studies revealed the genetic determinants of canine narcolepsy, an autosomal recessive gene we termed canarc1. Emmanuel Mignot took over the colony in 1986 and began sequencing DNA, finally isolating canarc1 in 1999.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The hypocretins (orexins) are a newly identified (1998) peptide family comprised of two peptides, hypocretin-1 and hypocretin-2. Recent observations suggest an involvement of these peptides, located primarily in the hypothalmus, in the regulation of behavioral state. They are involved in circadian rhythms, metabolism, hormone secretion, body temperature, appetite, cardiovascular functions (e.g., blood pressure), and sleep abnormalities (e.g., narcolepsy and cataplexy).

Taschenbuch. Zustand: Neu. Behavioral Neuroscience of Orexin/Hypocretin | Andrew J Lawrence (u. a.) | Taschenbuch | Current Topics in Behavioral Neurosciences | viii | Englisch | 2018 | Springer | EAN 9783319861876 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This issue of Current Topics in Behavioral Neuroscience focuses on the neuropeptide orexin (hypocretin) and brings together scientists from around the world who willprovide a timely discussion of how this peptide regulates behavior. This is a fast-moving field, and with the incorporation of novel technologies, new breakthroughs are likely to continue. For example, the use of optogenetic approaches has enabled the identification of the role of orexin-containing neurons in arousal states, critical for higher order functioning. From a clinical perspective, genetic polymorphisms in hypocretin/orexin and orexin receptors are implicated in a number of psychiatric disorders. In addition, advanced clinical trials are currently underway for orexin receptor antagonists in the treatment of insomnia and sleep disorders. We aim to capture a broad audience of basic scientists and clinicians.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This issue of Current Topics in Behavioral Neuroscience focuses on the neuropeptide orexin (hypocretin) and brings together scientists from around the world who willprovide a timely discussion of how this peptide regulates behavior. This is a fast-moving field, and with the incorporation of novel technologies, new breakthroughs are likely to continue. For example, the use of optogenetic approaches has enabled the identification of the role of orexin-containing neurons in arousal states, critical for higher order functioning. From a clinical perspective, genetic polymorphisms in hypocretin/orexin and orexin receptors are implicated in a number of psychiatric disorders. In addition, advanced clinical trials are currently underway for orexin receptor antagonists in the treatment of insomnia and sleep disorders. We aim to capture a broad audience of basic scientists and clinicians.

Hardcover. Zustand: Brand New. 322 pages. 9.25x6.10x0.87 inches. In Stock.

Paperback. Zustand: Brand New. reprint edition. 322 pages. 9.25x6.10x0.75 inches. In Stock.

Rústica. Zustand: Como nuevo. 1ª ed. 16.5x24. 3 vols. de 160pp. 2h.; 516pp. 2h.; 148pp. Rústica. Souto Alabarce, Arturo; Ruiz-Funes, Concepción; Pla Brugat, Dolores; Perea, Héctor; Díaz de Guereñu, Juan Manuel; Gil Villegas, Francisco; Pérez de Ayala, Juan; Garciadiego Dantan, Javier; Hernández de León-Portilla, Ascención; Matesanz, José A.; Soler, Martí; Corral, Rose; Serrano Migallón, Fernando; Naufal Tuena, Georgina; Baratas Díaz, Luis Alfredo; Valender, James; Rodríguez de Lecea, Teresa; Díaz Arciniega, Víctor; García Velasco, José; Alted Vigil, Alicia; Muñiz-Huberman, Angelina; Casados, Santos; Lira, Andrés; Sanchez Vidal, Agustín. José Luis Abellán; Juan Marichal; Rafael Segovia; Arturo Souto; Javier Garcíadiego; Francisco Gil Villegas; Josep Lluis Barona; Juan Manuel Díaz de Guereñu; Andrés Lira; José María Espinasa, James Valender, Paloma Altolaguirre, Patricica Hernández, Antonio Carreira y Carlos Blanco Aguinaga. Español. Muy buenos ejemplares.

Hardcover. Misura 8 ° (24,0: 16,4 cm). Magnifico cinturino in pelle rossa del tempo con titolo posteriore in oro stampato e ornamenti posteriori su quattro falsi tasti. Gli angoli inferiori sono leggermente urtati. 336 pagine con innumerevoli illustrazioni di testo in bianco e nero e due a colori (pagina 42 e 124) e dieci pannelli (pagine 16, 54, 80, 144, 176, 208, 240, 282, 324 e 326). Esattamente controllato fianco a fianco. Per lo più pulito. Difficile nel blocco. Buona copia -- Gr.-8° ( 24,0 : 16,4 cm). Prächtiger roter Halblederband der Zeit mit goldgeprägtem Rückentitel und Rückenverzierungen auf vier falschen Bünden. Unteren Ecken etwas bestoßen. 336 Seiten mit unzähligen schwarz-weißen und zwei farbigen ( S.42 und 124) Textabbildungen sowie und zehn Tafeln (S. 16, 54, 80, 144, 176, 208, 240, 282, 324 und 326). Seite für Seite genau überprüft. Überwiegend sauber. Fest im Block. Gutes Exemplar. Con la paginazione consecutiva i numeri sono datati da gennaio a settembre 1909, i seguenti numeri da ottobre a dicembre, comunque con il 1910! -- Bei fortlaufender Paginierung sind die Hefte Januar bis September 1909 datiert, die folgenden Hefte Oktober bis Dezember jedoch mit 1910! -- Bitte Portokosten außerhalb EU erfragen! / Please ask for postage costs outside EU! / S ' il vous plait demander des frais de port en dehors de l ' UE! // Bitte beachten Sie auch unsere Fotos! / Please also note our photos! / Veuillez noter nos photos -- Nehmen Sie sich ein gutes Buch mit auf die Sommerwiese. Bei uns werden Sie fündig! -- Wir kaufen Ihre werthaltigen Bücher! Hera.