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In den WarenkorbPaperback. Zustand: Brand New. 370 pages. 9.21x6.14x0.87 inches. In Stock.
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Sprache: Englisch
Verlag: Springer Berlin Heidelberg, 2011
ISBN 10: 3642749798 ISBN 13: 9783642749797
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Taschenbuch. Zustand: Neu. Therapeutic Interventions in the Complement System | John D. Lambris (u. a.) | Taschenbuch | Contemporary Immunology | x | Englisch | 2012 | Humana | EAN 9781468496123 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
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Zustand: New. Editor(s): D Lambris, John; Holers, V.Michael. Series: Contemporary Immunology. Num Pages: 270 pages, 23 black & white illustrations. BIC Classification: WM. Category: (G) General (US: Trade). Dimension: 229 x 152 x 14. Weight in Grams: 402. . 2000. Softcover reprint of the original 1st ed. 2000. Paperback. . . . . Books ship from the US and Ireland.
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Zustand: New. Reviews complement's basic biology, its role in disease, methods to measure its activity, and strategies for its inhibition in patients. This work highlights for the researcher effective strategies of drug discovery and development that are producing new complement inhibitors for the treatment of a variety of clinically important diseases. Editor(s): Lambris, JD (University of Pennsylvania School of Medicine, Philadelphia, PA USA); Holers, VM (University of Colorado Health Sciences Center, Denver, CO, USA). Series: Contemporary Immunology. Num Pages: 270 pages, biography. BIC Classification: MJCM; PSBC; PSBM. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 19. Weight in Grams: 1260. . 2000. Hardback. . . . . Books ship from the US and Ireland.
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The third component of complement, C3, is one of the most versatile proteins and an important participant in immune surveillance and immune response pathways. Its multifunctio nality is based on its ability to interact specifically with multiple serum complement proteins, cell surface receptors, and mem brant;-associated regulatory proteins. One of its most intriguing strategies of interaction with cell surfaces is the covalent binding of activated C3 through the internal thioester. The field has expanded over the past 10 years and a wealth of information has accumulated. C3 from various species and many of the human C3 binding proteins have been cloned and expressed. Numerous cellular responses mediated by the diffe rent fragments of C3 have been described. The findings that C3 interacts in a ligand-receptor-like fashion with proteins of nonself origin such as the gC of herpes simplex virus, a 70-kDa protein from Candida albicans, proteins from Epstein-Barr virus, etc. has opened a new field of investigation. The papers assembled in this volume summarize the wealth of data on the various aspects of the C3 interactions; together they bring to the reader new information on the chemistry, molecular gene tics, biology, and pathophysiology of C3 and C3-binding proteins. Emphasis is given to structural features as they relate to functions. Spring 1989 JOHN D. LAMBRIS, HANS J. MULLER-EBERHARD Table of Contents J. E. VOLANAKIS: Participation of C3 and Its Ligands in Complement Activation . . . . . . . . . . . 1 S. R. BARNUM, G. FEY, and B. F. TACK: Biosynthesis and Genetics of C3 . . . . . . . . . . . . .
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In den WarenkorbZustand: Used. pp. 460 Illus.
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In den WarenkorbPaperback. Zustand: Brand New. 275 pages. 9.20x6.10x0.88 inches. In Stock.
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Sprache: Englisch
Verlag: Springer US, Springer New York, 2013
ISBN 10: 1461429528 ISBN 13: 9781461429524
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Mounting evidence in the past decade indicates that innate immunity mediates functions above and beyond first-line defense against infection. It is now appreciated that innate immune mechanisms are critically involved in the development of adaptive immunity and, moreover, the regulation of diverse physiological and homeostatic processes. The latter explains why deregulation of innate immunity may lead to pathological disorders that are not necessarily or directly related to host defense.This Volume compiles the latest advances in this rapidly evolving field as presented by eminent scientists at the 7th International Aegean Conference on Innate Immunity in Rhodes, Greece. It includes topics related to the biology and function of Toll-like and other pattern-recognition receptors, complement and its crosstalk with other physiological systems, inflammatory mechanisms and diseases, natural killer cells, and the cooperative interplay between innate and adaptive immune cells. This book is an excellent source of information for researchers and clinicians with interests in immunology, host-microbe interactions, and infectious and inflammatory diseases.
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Taschenbuch. Zustand: Neu. Complement Therapeutics | John D. Lambris (u. a.) | Taschenbuch | viii | Englisch | 2016 | Springer | EAN 9781489978233 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
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