kenneth maiese (33 Ergebnisse)

Zustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Zustand: New. pp. 512.

Zustand: New. pp. 512.

Zustand: New. pp. 350.

Paperback. Zustand: Brand New. 512 pages. 10.87x8.50x1.30 inches. In Stock.

Paperback. Zustand: Brand New. 350 pages. 10.88x8.50x0.71 inches. In Stock.

PAP. Zustand: New. New Book. Shipped from UK. Established seller since 2000.

PAP. Zustand: New. New Book. Shipped from UK. Established seller since 2000.

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Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 472 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.

Zustand: Hervorragend. Zustand: Hervorragend | Seiten: 472 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.

Zustand: New. pp. xiv + 305 Illus.

Taschenbuch. Zustand: Neu. Forkhead Transcription Factors | Vital Elements in Biology and Medicine | Kenneth Maiese | Taschenbuch | 292 S. | Englisch | 2012 | Springer | EAN 9781461424895 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Buch. Zustand: Neu. Neuware -Galen in the 2nd century AD could be considered one of the earliest researchers who attempted to bridge the gap between basic science and clinical medicine. Galen is given initial credit for the recognition that vital organs of the body are exquisitely dependent upon the intact function of the circulatory system. The doctrines of Galenic physiology stated that blood was produced in the liver, flowed to the heart to obtain 'vital spirits', and subsequently bathed the brain to gain 'animal spirits'. The 'vital spirits' described by Galen were later disclosed to consist of oxygen. Oxygen was discovered independently by Schiele in Sweden and by Priestly in England. It was named oxygen (acid-former) by Antoine Lavoisier (1743-1794) of France. Lavoisier made significant medical discoveries concerning oxygen's role in respiration. In animal experiments, Lavoisier and others discovered that anoxia could rapidly lead to death. The initial work by these investigators helped provide direction for modern clinical science and the treatment of disease, especially concerning disorders of the nervous system. Remarkably, our understanding of human disease continues to grow at an exponential rate. At times, the accumulation of knowledge of the cellular components of clinical disease exceeds all prior expectations held just a few years ago, such as evidenced by the recent cloning of the human and mouse genomes. Despite theses advances, both biomedical scientists and clinicians sometimes are at a loss to recognize the crucial link between basic science discovery and the development of therapeutic regiments for clinical disease.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 328 pp. Englisch.

Zustand: New. KENNETH MAIESE is a physicianscientist whose interests focus on the basic and clinical mechanisms that control neuronal and vascular longevity and immune system function. He presently is the Chief of the Division of Cellular and Molecular Cerebral Ischem.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Forkhead Transcription Factors: Vital Elements in Biology and Medicine provides a unique platform for the presentation of novel work and new insights into the vital role that forkhead transcription factors play in multiple systems throughout the body. Leading international authorities provide their knowledge and insights to offer a novel perspective for translational medicine that highlights the role of forkhead genes and proteins that may have the greatest impact for the development of new strategies for a broad array of disorders. Equally important, Forkhead Transcription Factors: Vital Elements in Biology and Medicine clearly sets a precedent for the necessity to understand the diverse and complex nature of forkhead proteins since this family of transcription factors can limit as well as foster disease progression depending upon the cellular environment. The presentation and discussion of innovative studies and especially those that examine previously unexplored pathways that may influence clinical survival and longevity offer an exciting approach to address the potential of forkhead transcription factors for new therapeutic avenues in multiple disciplines.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Galen in the 2nd century AD could be considered one of the earliest researchers who attempted to bridge the gap between basic science and clinical medicine. Galen is given initial credit for the recognition that vital organs of the body are exquisitely dependent upon the intact function of the circulatory system. The doctrines of Galenic physiology stated that blood was produced in the liver, flowed to the heart to obtain 'vital spirits', and subsequently bathed the brain to gain 'animal spirits'. The 'vital spirits' described by Galen were later disclosed to consist of oxygen. Oxygen was discovered independently by Schiele in Sweden and by Priestly in England. It was named oxygen (acid-former) by Antoine Lavoisier (1743-1794) of France. Lavoisier made significant medical discoveries concerning oxygen's role in respiration. In animal experiments, Lavoisier and others discovered that anoxia could rapidly lead to death. The initial work by these investigators helped provide direction for modern clinical science and the treatment of disease, especially concerning disorders of the nervous system. Remarkably, our understanding of human disease continues to grow at an exponential rate. At times, the accumulation of knowledge of the cellular components of clinical disease exceeds all prior expectations held just a few years ago, such as evidenced by the recent cloning of the human and mouse genomes. Despite theses advances, both biomedical scientists and clinicians sometimes are at a loss to recognize the crucial link between basic science discovery and the development of therapeutic regiments for clinical disease.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Galen in the 2nd century AD could be considered one of the earliest researchers who attempted to bridge the gap between basic science and clinical medicine. Galen is given initial credit for the recognition that vital organs of the body are exquisitely dependent upon the intact function of the circulatory system. The doctrines of Galenic physiology stated that blood was produced in the liver, flowed to the heart to obtain 'vital spirits', and subsequently bathed the brain to gain 'animal spirits'. The 'vital spirits' described by Galen were later disclosed to consist of oxygen. Oxygen was discovered independently by Schiele in Sweden and by Priestly in England. It was named oxygen (acid-former) by Antoine Lavoisier (1743-1794) of France. Lavoisier made significant medical discoveries concerning oxygen's role in respiration. In animal experiments, Lavoisier and others discovered that anoxia could rapidly lead to death. The initial work by these investigators helped provide direction for modern clinical science and the treatment of disease, especially concerning disorders of the nervous system. Remarkably, our understanding of human disease continues to grow at an exponential rate. At times, the accumulation of knowledge of the cellular components of clinical disease exceeds all prior expectations held just a few years ago, such as evidenced by the recent cloning of the human and mouse genomes. Despite theses advances, both biomedical scientists and clinicians sometimes are at a loss to recognize the crucial link between basic science discovery and the development of therapeutic regiments for clinical disease.

Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 488 | Sprache: Englisch | Produktart: Bücher.

Zustand: New. Chapters are authored by internationally recognized experts who elucidate the intimate relationship between cancer and metabolic disease that intersects with sirtuin pathways Presents the basic and clinical role of sirtuins in regard to ca.

Paperback. Zustand: Brand New. 292 pages. 9.20x6.10x0.66 inches. In Stock.

Paperback. Zustand: Brand New. reprint edition. 322 pages. 9.25x6.10x0.77 inches. In Stock.

Hardcover. Zustand: Brand New. 1st edition. 269 pages. 10.25x6.75x1.00 inches. In Stock.

Hardcover. Zustand: Brand New. 1st edition. 328 pages. 9.25x6.25x0.75 inches. In Stock.

Buch. Zustand: Neu. Neuware.

Zustand: New. 2021. Paperback. . . . . . Books ship from the US and Ireland.

Taschenbuch. Zustand: Neu. Neuware - Sirtuin Biology in Cancer and Metabolic Disease: Cellular Pathways for Clinical Discovery offers a compelling and thought-provoking perspective for the examination of the intriguing biology of sirtuins that ties cancer and metabolic disease together and provides a critical platform for the development of sirtuin-based novel therapeutic strategies to effectively treat cancer and metabolic disorders with precision in order to minimize any potentially detrimental clinical outcomes. An exciting prospect for the development of innovative therapeutics for cancer and metabolic disorders involves sirtuins. Sirtuins are histone deacetylases that have an intricate role in the onset and development of cancer and metabolic disease. Implementing a translational medicine format, this innovative reference highlights the ability of sirtuins to oversee critical pathways that involve stem cell maintenance, cellular proliferation, metabolic homeostasis, apoptosis, and autophagy that can impact cellular dysfunction and unchecked cellular growth that can occur during cancer and metabolic disease. Each chapter offers an intuitive perspective of advances on the application of sirtuin pathways for cancer and metabolic disease that will be become a 'go-to' resource for a broad audience of scientists, physicians, pharmaceutical industry experts, nutritionists, and students.

Buch. Zustand: Neu. Neuware -Features that characterize the aging process include the gradual accumulation of cell damage after prolonged exposure to oxidative and inflammatory events over a lifetime. In addition to the accretion of lesions, the intrinsic levels of pro-oxidant and aberrant immune responses are elevated with age. These adverse events are often further enhanced by the chronic and slow progressing diseases that characterize the senescent brain and cardiovascular system. The incidence of some disorders such as Alzheimer's disease and vascular diseases are sufficiently prevalent in the extreme elderly that these disorders can arguably be considered 'normal'.Aging and Aging-Related Disorders examines the interface between normal and pathological aging, and illustrates how this border can sometimes be diffuse. It explores and illustrates the processes underlying the means by which aging becomes increasingly associated with inappropriate levels of free radical activity and how this can serve as a platform for the progression of age-related diseases.The book provides chapters that examine the interactive relationship between systems in the body that can enhance or sometimes even limit cellular longevity. In addition, specific redox mechanisms in cells are discussed.Another important aspect for aging discussed here is the close relationship between the systems of the body and exposure to environmental influences of oxidative stress that can affect both cellular senescence and a cell¿s nuclear DNA. What may be even more interesting to note is that these external stressors are not simply confined to illnesses usually associated with aging, but can be evident in maturing and young individuals.A broad range of internationally recognized experts have contributed to this book. Their aim is to successfully highlight emerging knowledge and therapy for the understanding of the basis and development of aging¿related disorders.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 488 pp. Englisch.

Taschenbuch. Zustand: Neu. Sirtuin Biology in Cancer and Metabolic Disease | Cellular Pathways for Clinical Discovery | Kenneth Maiese | Taschenbuch | Englisch | 2021 | Elsevier Science | EAN 9780128224670 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu.

Zustand: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher.