hook jerry (12 Ergebnisse)

Hardcover. Zustand: Very Good. No Jacket. May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend Less.

Hardcover. Zustand: Very Good. No Jacket. Hardcover 1986 edition. Ex-library book with stamps and labels attached. Binding firm. Minor underlining to page 154, otherwise pages unmarked and clean. Covers very good. Series : Developments in Toxicology and Environmental Science ;Vol. 14 .[256 p. : ill. ; 25 cm].

Zustand: New. In.

Zustand: New. In.

Hardcover. Zustand: Very Good. Series: New Horizons in Therapeutics xxii 488p hardback with green laminated boards, fresh clean copy, library stamp, very good indeed Language: English.

Zustand: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,950grams, ISBN:0306434636.

hardcover. Zustand: Very Good. Zustand des Schutzumschlags: No Dust Jacket. Second Edition. numerous figures and tables, gilt lettering to spine and front cover, lightly rubbed tail of spine, text clean and tight. Ex-Library.

Zustand: New. In.

Paperback. Zustand: Brand New. reprint edition. 534 pages. 9.02x5.98x1.17 inches. In Stock.

Taschenbuch. Zustand: Neu. Protein Design and the Development of New Therapeutics and Vaccines | Jerry B. Hook (u. a.) | Taschenbuch | xxii | Englisch | 2012 | Springer | EAN 9781468457414 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - InhaltsangabeI. Advances in the Structural Analysis of Proteins.- 1 Dynamic Processes in Proteins by X-Ray Diffraction.- 1. Dynamic Processes in Proteins.- 2. Enzyme Substrate Complexes by X-Ray Diffraction.- 3. Laue Diffraction.- 4. Reaction Synchronization.- References.- 2 Mass Spectrometric Methods for Determination of the Structure of Peptides and Proteins.- 1. Introduction.- 2. High-Mass Mass Spectrometry.- 3. Tandem Mass Spectrometry.- 3.1. Sequencing of Proteins.- 3.2. Increasing Sensitivity by Using an Array Detector.- 3.3. Computer-Aided Interpretation of CID Spectra of Peptides.- 4. Conclusion.- References.- II. Protein Folding and Stability.- 3 Protein Folding and Stability.- 1. Goals.- 2. Folding of Fragments.- 3. Trapping Folding Intermediates.- References.- 4 Genetic Analysis of Polypeptide Chain Folding and Misfolding in Vivo.- 1. Introduction.- 2. The Protein Folding Grammar.- 3. Intracellular Intermediates in Chain Folding and Assembly.- 4. Temperature-Sensitive Folding Mutations.- 5. Nonsense Mutations.- 6. Intracellular Aggregation and Inclusion Body Formation.- 7. Kinetics of Aggregate Formation.- 8. Isolation of Second-Site Suppressors of Folding Mutants.- 9. The Suppressing Amino Acid Substitutions Act at the Level of Polypeptide Chain Maturation.- 10. The Suppressors Act in the Folding of the Single Chain, Not during Chain-Chain Association.- 11. The Suppressors Increase the Efficiency of Folding of the Wild-Type Chain.- References.- 5 Unfolding and Inactivation: Genetic and Chemical Approaches to the Stabilization of T4 Lysozyme and Human Interferon Gamma against Irreversible Thermal Denaturation.- 1. Introduction.- 2. T4 Lysozyme.- 2.1. Sulfhydryl Oxidation.- 2.2. Thiol/Disulfide Interchange.- 2.3. Adsorption.- 2.4. Aggregation.- 2.5. Chemical Inactivation.- 2.6. Conclusions from T4 Lysozyme Experiments.- 3. Interferon- .- 3.1. In Vitro Experiments.- 3.2. Genetic Experiments.- 4. General Conclusions.- 4.1. Modes of Thermal-Irreversible Denaturation.- 4.2. Strategies for Stabilizing Proteins.- References.- III. Principles of Receptor Design and Regulation.- 6 Protein-Tyrosine Kinases and Their Substrates: Old Friends and New Faces.- 1. Introduction.- 2. Isolation of Novel Protein-Tyrosine Kinases.- 3. Regulation of Protein-Tyrosine Kinase Activity: Phosphorylation of pp60c-src.- 4. Protein-Tyrosine Kinase Substrates.- References.- IV. The Guanine Nucleotide Binding Protein Family.- 7 G Proteins: A Family of Signal-Transducing Molecules.- 1. The Family of G Proteins.- 2. Distribution of G Protein Subunits.- 3. Regulation of o Levels.- 4. G Proteins as Bifurcating Signals.- 5. Organizing Principles.- References.- 8 Model of Signal Transduction by G Proteins: Roles of a Subunits and Dimers in Regulation of Ionic Channels and Adenylyl Cyclase.- 1. Introduction.- 2. Mechanisms of Receptor-Mediated Activation of G Proteins.- 3. Which G-Protein Subunit Mediates the Effect of Receptors .- 3.1. Regulation of Ionic Channels: or , and What Does Each Do to Regulation of Channel Activity .- 3.2. Inhibitory Regulation of Adenylyl Cyclase: i or .- 3.3. What Is the Role of Dimers .- References.- 9 Structural Homologies in G-Binding Proteins.- 1. Introduction.- 2. Structural Homology in Three Dimensions.- 2.1. Elongation Factor Tu (EF-Tu).- 2.2. ras Protein p21.- 3. Sequence Homology.- 3.1. Overall Homology.- 3.2. Consensus Sequences.- 4. Homology and Functional Similarity.- References.- V. Modeling and Structure Prediction in Macromolecules.- 10 Knowledge-Based Protein Modeling and the Design of Novel Molecules.- 1. Introduction.- 2. Learning by Comparison of Structures.- 2.1. Superposition of Structures.- 2.2. Comparison of Properties and Relations.- 2.3. Clustering and Tree Construction.- 3. Rules for Tertiary Templates and Key Residues, and Their Comparison with a Sequence of an Unknown.- 3.1 Consensus Sequences for Framework Regions.- 3.2. Key Residues from Comparisons of Properties and Relations.- 3.3. Charact.

Second edition. orig. cloth Minor rubbing.Small label to rear cover.Light page-edge soil.VG. Textual photos & tables. 24x16cm, xiii,558 pp, Series: Target Organ Toxicology Series. Contains 19 papers. Includes: L.B. Kinter & B.G. Short "Anatomy and Physiology of the Kidney: A Brief Review"; E.C. Foulkes "Functional Assessment of the Kidney"; W.M. Bennet & G.A. Porter "Overview of Clinical Nephrotoxicity"; S. Olsen & K. Solez "Morphological Features of Acute Renal Failure"; M. Brezis & F.H. Epstein "Pathophysiology of Acute Renal Failure"; M. Abbate; D. Macconi & G. Remuzzi "Mechanisms of Glomerular Injury"; R.S. Goldstein "Biochemical Heterogeneity and Site-Specific Tubular Injury"; J.J. Weening "Nephrotoxicity of Protein Overloading"; B.M.Tune "The Nephrotoxicity of Beta-Lactam Antibiotics"; R.F. Borch "The Nephrotoxicity of Antineoplastic Drugs"; G.F. Duggin "Analgesic Nephrotoxicity"; L.C. Racusen & K. Solez "Nephrotoxicity of Cylosporine and Other Immunosuppressive and Immunotherapeutic Agents"; G.L. Bakris Pathogenesis and Therapeutic Aspects of Radiocontrast-Induced Renal Dysfunction"; A.A. Elfarra "Aliphatic Halogenated Hydrocarbons"; S.S. Lau &T.J. Monks "Nephrotoxicity of Bromobenzene: The Role of Quinone- Thioethers"; E.A: Conner & B.A. Fowler "Mechanisms of Metal-Induced Nephrotoxicity"; W.O. Berndt "Effects of Selected Fungal Toxins on Renal Function"; L.D. Lehman-McKeeman "Male Rat-Specific Light Hydrocarbon Nephropathy"; D.R. Dietrich & J.A. Swenberg "Renal Carcinogenesis". Minor rubbing.Small label to rear cover.Light page-edge soil.VG.