Graham rook (9 Ergebnisse)

Hardcover. Zustand: Very Good. Zustand des Schutzumschlags: Very Good. First Edition. Publisher's hardback in very good condition: firm, square and tight with no snags or splits, just a trifle rubbed. Complete with original dustjacket: in decent shape, just slightly rubbed and moderately edge-worn. Contents sound and clean; no pen-marks, just a Medical College bookplate at the endpaper. Thus a tidy book in presentable condition. …

Pp. Zustand: Sehr gut. XII, 305 S. : Ill., graph. Darst. ; 24 cm Die Kernaussage: Moderne Lebensbedingungen reduzieren die Exposition gegenüber Mikroorganismen mit Folgen für die Regulation des Immunsystems und die Zunahme chronisch-entzündlicher Erkrankungen. Die Pämisse: Rook beschreibt, dass der Übergang vom Jäger-Sammler-Leben zu modernen Industriegesellschaften die Mikrobenexposition drastisch reduziert hat. Dies führt zu Fehlregulationen des Immunsystems und damit zu einem Anstieg von: allergischen Erkrankungen, Autoimmunerkrankungen, entzündlichen Darmerkrankungen, Atherosklerose, Depressionen mit entzündlicher Komponente, möglicherweise, Alzheimer und Parkinson. Die Hygienehypothese wird in einen evolutionären Kontext gestellt: Der menschliche Organismus ist an eine Umwelt angepasst, in der dauerhafte mikrobielle Stimulation normal war. Das moderne Mikroben-Defizit erzeugt evolutionär unpassende Immunreaktionen. Der Autor verbindet bei seinem Denkweg mikrobiologische Evolutionsgeschichte, Immunologie, Epidemiologie, klinische Beispiele aus vielen Organsystemen, therapeutische Perspektiven. Sprache: Englisch Gewicht in Gramm: 855.…

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This edited collection of 12 chapters by research workers from a wide range of disciplines resolves the confusion that currently surrounds the 'hygiene hypothesis' by considering the human need for exposure to microorganisms from an evolutionary point of view. The book explains why we evolved a requirement for exposure to microbiota from our mothers, from other people, and from the natural environment. It also explains the physiological roles of these exposures, what goes wrong when the exposures are distorted and how human lifestyles and activities, including degradation of the natural environment, are leading to this distortion. Particular attention is given to the range of pathologies associated with inappropriate microbial exposures and inappropriate colonization, including immunoregulatory problems such as allergies and autoimmunity, metabolic problems such as obesity and diabetes, and problems of central nervous system function and neurodegeneration. This book is of profound relevance to most medical disciplines, but also to those concerned with preserving the natural environment and with developing healthier urbanisation.…

Zustand: New. In English.

Zustand: gut. 2009. The Hygiene Hypothesis and Darwinian Medicine (Progress in Inflammation Research) In deutscher Sprache. pages.

Hardcover. Zustand: Brand New. 424 pages. 9.25x6.10x0.87 inches. In Stock.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Man has moved rapidly from the hunter-gatherer environment to the living conditions of industrialised countries. The hygiene hypothesis suggests that the resulting reduced exposure to micro-organisms has led to disordered regulation of the immune system, and hence to increases in certain chronic inflammatory disorders, like allergic disorders, autoimmunity, inflammatory bowel disease, atherosclerosis, depression, some cancers and perhaps Alzheimer and Parkinson. This book discusses the evidence for and against in the context of Darwinian medicine, which uses knowledge of evolution to cast light on human diseases. The approach is interdisciplinary, looking at man's microbiological history, at the biology of the effects of microorganisms on the immune system, and at the implications for chronic inflammatory disorders in multiple organ systems. Finally, the authors describe progress in the exploitation of microorganisms or their components as novel prophylactics and treatments.…

Hardcover. Zustand: Brand New. 1st edition. 317 pages. 9.21x6.61x0.94 inches. In Stock.

Zustand: New. This book takes an interdisciplinary approach in discussing the evidence for and against the so-called 'hygiene hypothesis'. It does so in the context of Darwinian medicine, which deploys our knowledge of evolution in an effort to cast light on human diseases. Series: Progress in Inflammation Research. Num Pages: 308 pages, 10 black & white tables, biography. BIC Classification: MJCJ; MJCM; MMFM. Category: (P) Professional & Vocational. Dimension: 244 x 170 x 23. Weight in Grams: 885. . 2009. Hardback. . . . . Books ship from the US and Ireland.…