Geraghty (Mehr als 1.700 Ergebnisse)

Paperback. Zustand: Fair. Original. The item might be beaten up but readable. May contain markings or highlighting, as well as stains, bent corners, or any other major defect, but the text is not obscured in any way.

Zustand: Good. Item in good condition. Textbooks may not include supplemental items i.e. CDs, access codes etc.

Paperback. Zustand: Good. Gripping, emotional and uplifting a novel about the true power of friendship. a tender, emotional and uplifting read I loved it Lucy Diamond A superb writer the Irish Jojo Moyes Irish Examiner.

Zustand: Good. Item in good condition. Textbooks may not include supplemental items i.e. CDs, access codes etc.

Zustand: Good. Item in very good condition! Textbooks may not include supplemental items i.e. CDs, access codes etc.

Zustand: Good. Item in good condition. Textbooks may not include supplemental items i.e. CDs, access codes etc.

Zustand: Acceptable. Item in good condition. Textbooks may not include supplemental items i.e. CDs, access codes etc.

Zustand: Acceptable. Item in good condition. Textbooks may not include supplemental items i.e. CDs, access codes etc.

Zustand: Good. Item in good condition. Textbooks may not include supplemental items i.e. CDs, access codes etc.

Zustand: Good. Item in good condition. Textbooks may not include supplemental items i.e. CDs, access codes etc.

Hardback. Zustand: Very Good. Advances in medicine have made possible better treatments for widespread, familiar human illnesses like cancer, diabetes, and heart disease. Yet there are thousands of much less common diseases, most of genetic origin, each classed as rare because it afflicts only a small number of people. These patient groups were long ignored by a pharmaceutical industry that judged them too small to provide a return on the investment needed to develop an effective remedy. Yet these orphaned diseases collectively caused misery and expense, often far greater than did more common ailments, for tens of millions of individuals and their families. Forty years ago, a revolution that transformed the prospects of patients with rare diseases was lit by three sparks. The passage of the 1983 U.S. Orphan Drug Act resulted from public pressure brought by rare disease patients, their families, and advocates. The AIDS epidemic triggered additional activism, compounded when patients with the rare disease hemophilia became HIV-positive after infusion of tainted blood products. And the third spark was the emergence in the early 1980s of biotechnology companies like Genentech, Amgen, and Biogen employing then-new genetic engineering instead of conventional approaches to pharmaceutical development. Soon after, Genzyme became the first company to develop a treatment for a rare genetic disorder, Gaucher disease, which would come to transform the industry. Jim Geraghty has been a passionate participant in the orphan drug revolution since its inception--a leader in the field as a strategy consultant, biotechnology executive, and venture entrepreneur. His book is in part a history, with eyewitness accounts of advances as they occurred and portraits of the pioneering scientists and physicians, tireless activists, and visionary business leaders who made the revolution happen. And it tells deeply personal stories of patients and parents willing to risk new, untried therapies. But Geraghty also uses his exceptional experience and vantage point to look forward to the immense promise of the newest technologies like gene therapy and gene editing for the treatment of patients today and tomorrow. He concludes with thoughtful consideration of important questions. Why do drugs to treat orphan diseases cost so much? How can we ensure they are affordable? How can their effectiveness be responsibly assessed? And how can access to them be expanded internationally? This book graphically and poignantly illustrates how far an important healthcare revolution has come and reminds us that if not nurtured, it could end before its immense promise has been fulfilled.…

Paperback. Zustand: Fair. First Edition. The item might be beaten up but readable. May contain markings or highlighting, as well as stains, bent corners, or any other major defect, but the text is not obscured in any way.

Paperback. Zustand: Good. One afternoon a hungry mosquito flies over a steamy swamp. Just behind her hovers a greedy dragonfly, and behind the dragonfly waits a famished frog. . . . And so the story goes, with each hungry creature too intent on its dinner to be aware of the danger stalking it from behind.…

Paperback. Zustand: Fair. One afternoon a hungry mosquito flies over a steamy swamp. Just behind her hovers a greedy dragonfly, and behind the dragonfly waits a famished frog. . . . And so the story goes, with each hungry creature too intent on its dinner to be aware of the danger stalking it from behind.…

Paperback. Zustand: Very Good.

Zustand: Good. Item in very good condition! Textbooks may not include supplemental items i.e. CDs, access codes etc.

Hardback. Zustand: Good. The New York Times-bestselling author of The Eagle Has Landed delivers a pulse-pounding story of a father out for revenge against a master assassin. John Mikali is known throughout the world as a brilliant concert pianist and playboy. But his true vocation is far more interesting and lucrative: He is a peerless international assassin. His music and fame give him entr e to complete his assignments all over the world without fail. He believes himself truly untouchable--until he makes one fatal mistake. Col. Asa Morgan is a military man to the bone. A veteran of wars both declared and undeclared, he's one of the most respected and lethal members of the British SAS, and utterly devoted to his country. But when his daughter is run down and killed by an unknown assassin making his escape, his sworn duty no longer matters. Now, his only mission is to find the killer before the authorities do--and make him suffer as long as possible before death. Morgan and Mikali will stalk each other across continents, from bloody back alleys to gilded halls in a deadly game in which each man is both the hunter and the hunted. And only the winner walks away. Recognized as one of the finest thriller writers of our time, the international bestselling author of the Sean Dillon and Liam Devlin series delivers unadulterated macho adventure (and) suspense (Houston Post).…

Hardback. Zustand: Fair. The New York Times-bestselling author of The Eagle Has Landed delivers a pulse-pounding story of a father out for revenge against a master assassin. John Mikali is known throughout the world as a brilliant concert pianist and playboy. But his true vocation is far more interesting and lucrative: He is a peerless international assassin. His music and fame give him entr e to complete his assignments all over the world without fail. He believes himself truly untouchable--until he makes one fatal mistake. Col. Asa Morgan is a military man to the bone. A veteran of wars both declared and undeclared, he's one of the most respected and lethal members of the British SAS, and utterly devoted to his country. But when his daughter is run down and killed by an unknown assassin making his escape, his sworn duty no longer matters. Now, his only mission is to find the killer before the authorities do--and make him suffer as long as possible before death. Morgan and Mikali will stalk each other across continents, from bloody back alleys to gilded halls in a deadly game in which each man is both the hunter and the hunted. And only the winner walks away. Recognized as one of the finest thriller writers of our time, the international bestselling author of the Sean Dillon and Liam Devlin series delivers unadulterated macho adventure (and) suspense (Houston Post).…

Mass Market Paperback. Zustand: Fair. The item might be beaten up but readable. May contain markings or highlighting, as well as stains, bent corners, or any other major defect, but the text is not obscured in any way.

Paperback. Zustand: Very Good. It's a well-cared-for item that has seen limited use. The item may show minor signs of wear. All the text is legible, with all pages included. It may have slight markings and/or highlighting.

Zustand: Acceptable. Item in acceptable condition! Textbooks may not include supplemental items i.e. CDs, access codes etc.

Hardcover. Zustand: Fair. First US. The item might be beaten up but readable. May contain markings or highlighting, as well as stains, bent corners, or any other major defect, but the text is not obscured in any way.

Paperback. Zustand: Fair. Reprint. The item might be beaten up but readable. May contain markings or highlighting, as well as stains, bent corners, or any other major defect, but the text is not obscured in any way.

Hardcover. Zustand: Fair. The item might be beaten up but readable. May contain markings or highlighting, as well as stains, bent corners, or any other major defect, but the text is not obscured in any way.

Paperback. Zustand: Fair. First Edition. The item might be beaten up but readable. May contain markings or highlighting, as well as stains, bent corners, or any other major defect, but the text is not obscured in any way.

Zustand: Good. Item in good condition. Textbooks may not include supplemental items i.e. CDs, access codes etc.

Paperback. Zustand: Very Good. The spellbinding mock history of the Department of Agriculture's most secretive and vital agency. The little-known USDA Agency of Invasive Species--founded by President and humble peanut farmer Jimmy Carter--would like to reassure you that they rank among the most effective and cost-efficient offices within the sprawling federal bureaucracy. For decades, under Administrative Director Adam Humphrey and his "strategic disengagement" approach, the Agency has epitomized vigilance against the clear and present danger of noxious weeds. Humphrey's record of triumphant inertia faces only two obstacles. The first is reality; the second is the loud critic who dares to question the magic behind the Agency's success: Nicholas Bader. Formerly known as President Reagan's "bloody right hand," Bader is on an obsessive quest to trim the fat from the federal budget. Full of oddball characters who shed light on the daily operations of Beltway minions, The Weed Agency showcases a world in which federal budgets balloon every year, where a career can be built upon the skill of rationalizing astronomical expenses, and where the word "accountability" sends roars of laughter through DC office buildings. That's life inside the federal Agency of Invasive Species. and it may sound suspiciously similar to your reality.…

Paperback. Zustand: Fair. A thoroughly updated history of the legendary French Foreign Legion by the bestselling author of Who Dares Wins Tony Geraghty analyses the legend and re-examines the battle honours of the Foreign Legion, and his revelations illuminate the darker side of its historic relationship to the motherland. Called into being in 1831 as a device to absorb the footloose veterans of Napoleon?s old armies, the French Foreign Legion subsequently won astonishing victories in the farflung battlefields of Spain, the Crimea, Algeria and Morrocco, Italy, Mexico, Syria, Indo-China, Madagascar, and West and Central Africa. March or Die also traces the Legion's diminished fortunes in recent years. It has fought in the Gulf War, Rwanda and Kosovo among other conflicts, but has found itself in 'a world of political correctness which left the Legion marooned on an island of admirable but anachronistic values'. Forced to accept women in its ranks and no longer unique now that conscription has been abolished, it is searching for its place in the modern world.…

Paperback. Zustand: Very Good. First Edition. It's a well-cared-for item that has seen limited use. The item may show minor signs of wear. All the text is legible, with all pages included. It may have slight markings and/or highlighting.

Hardback. Zustand: Good. What has happened to men in America? Once upon a time, men in their twenties looked forward to settling down and having children. Today, most young men seem infected by a widespread Peter Pan syndrome. Unwilling to give up the freedom to sleep late, play video games, dress like a slob, and play the field, today?s men wallow in an extended adolescence, ostensibly unaware that they?re setting themselves up for a depressing, lonely existence.In this hilarious ode to male adulthood, Jim Geraghty and Cam Edwardstwo happily married, 40-year-old menhave a simple message for their younger peers: Grow up.…