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Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 218 | Sprache: Englisch | Produktart: Bücher.

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Taschenbuch. Zustand: Neu. Neuware -Following 50 years of glucocorticoid use in a clinical setting, aninternational body of expert scientists and physicians presents the mostexpansive survey of glucocorticoid pharmacology to date. This worktraces the history of glucocorticoid biology from the seminaldescription of glucocorticoid insufficiency by Thomas Addison in themid-19th century, up to current advances in elucidating the molecularbasis of glucocorticoid action. Important discoveries are presented, aswell as milestones in drug development, a survey of current clinicalpractice, and prospects for novel glucocorticoid-based therapeutics.Scientists and clinicians will appreciate the scope of this work, whichis of special interest to workers in the fields of endocrinologyinflammation and autoimmune disease.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 220 pp. Englisch.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Following 50 years of glucocorticoid use in a clinical setting, an international body of expert scientists and physicians presents the most expansive survey of glucocorticoid pharmacology to date. This work traces the history of glucocorticoid biology from the seminal description of glucocorticoid insufficiency by Thomas Addison in the mid-19th century, up to current advances in elucidating the molecular basis of glucocorticoid action. Important discoveries are presented, as well as milestones in drug development, a survey of current clinical practice, and prospects for novel glucocorticoid-based therapeutics. Scientists and clinicians will appreciate the scope of this work, which is of special interest to workers in the fields of endocrinology, inflammation and autoimmune disease.

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Taschenbuch. Zustand: Neu. Neuware -Since the discovery of the pharmacological and toxicological importance of inhibiting the cyclooxygenase (COX) enzymes by non-steroidal anti-inflammatory drugs (NSAIDs), much research has gone into the development of methods to study the biological functions of COX-1 and COX-2. In Cyclooxygenases: Methods and Protocols, experts and pioneers in the field present the most up-to-date in vitro and in vivo techniques routinely used in COX research. The volume delves into essential topics such as the purification, cloning, and expression of COX enzymes as well as in vitro assays aimed at determining the inhibitory potency of drugs on COX-1 and COX-2 activities, with chapters describing protocols used for the extraction and measurement of the prostanoids. This volume also describes in vivo disease models used to study the roles of COX-1 and COX-2 in gastrointestinal injury, inflammation, and pain. As a book in the highly successful Methods in Molecular Biology¿ series, the protocols chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Cyclooxygenases: Methods and Protocols serves as an indispensable tool for all scientists seeking the treatment of inflammation, pain, fever, and other harmful conditions.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 228 pp. Englisch.

Zustand: New. In.

Zustand: New. In.