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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The present challenge in the treatment of tumors is to reduce the number of patients that still die as a result of primary tumors. Today, the percentage of such deaths remains high at 30%, even when all the common therapeutic methods, namely surgery, radiotherapy, and chemotherapy, are applied. In order to reduce this percentage, new types of radiation sources with a higher linear energy transfer have been intro duced, such as neutrons and pions. Fractionation patterns have been modified and radiosensitizers have been applied to in crease biological efficiency. Studies of the combined application of chemotherapy and radiotherapy have been made to find the best therapeutic effect. In the early 1970s biological findings confirmed the effect of hyperthermia on tumor cells. The first clinical studies on hyper thermia treatment demonstrated that it resulted in better local tumor control. Further application of this treatment modality showed that hyperthermia should be used in addition to radio therapy and chemotherapy. Despite these encouraging results, hyperthermia has not been introduced into common clinical use, due primarily to technical problems. There are a number of methods of transferring heat into tumors; however, with regard to physical conditions, an op timum method has not yet been found. One of the reasons is that up to now we have had no reliable method of obtaining thermal mapping of all parts of the human body. Such measurements are required not only for dosimetric purposes but also for the regula tion of a hyperthermic system.
Sprache: Englisch
Verlag: Springer Berlin Heidelberg, 2011
ISBN 10: 364284894X ISBN 13: 9783642848940
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Biologists and radiotherapists present their experimentalwork and clinical data in the field of radiation injuries ofnormal tissues and organs. Particular regard is payed to therelevance of biological mechanisms in clinical situations.Principles of radiation damage and combined treatmenttoxicity in radio-chemotherapy are being explained. The maintopics discussed are the importance of microvasculature,time, doseand fractionation and factors modifying clinicalradioresponse for early andlate radiation effects. Tissuesand organs considered in this volume are mucosa and skin,lung and heart, bladder and muscle, CNS and eye. Specialproblems of pediatric radiotherapy, TBI, IORT and secondmalignacies are also mentioned.
Sprache: Englisch
Verlag: Springer Berlin Heidelberg, 2012
ISBN 10: 3642832652 ISBN 13: 9783642832659
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Physicians and biologists here present their experimental work in the field of hyperthermia, paying particular regard to its relevance in clinical situations. Principles of heat action and combined treatment modalities are explicated. The main topics discussed are the effects of such treatment on normal tissues, animal tumors, malignant cell lines and human tumors.