breit samuel (8 Ergebnisse)

Hardcover. Zustand: Sehr gut. 24cm; ca. 250 S. Hardcover. Sprache: Englisch, Zustand: Sehr Gut eher ungelesen; Besitzerstempel; * Die Photos sind original von uns erstellt worden, u.a. erkennbar an einem kleinen weißen Stück Papier im oberen Schnitt. Ab und an verwenden Suchmaschinen Verlagsphotos, bei den Portalen selbst, werden aber nur unsere Originalphotos gezeigt.

Zustand: New. In.

Paperback. Zustand: Brand New. reprint edition. 220 pages. 9.20x6.10x0.52 inches. In Stock.

Zustand: New. In.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The TGF-13 superfamily is a large and expanding multigene family which in verte brates includes the TGF-13 proteins themselves, the bone morphogenetic proteins (BMPs), the growth and differentiation factors (GDF), the activins/inhibins (INH), Mullerian inhibitory substance (MIS), glial derived neurotropic factor (GDNF) and more recently macrophage inhibitory cytokine 1 (MIC-1). They are characterised by conserved structural elements and a broad commonality of function. Major structural elements All members of the TGF-13 superfamily contain as their major structural hallmark a conserved spacing and distribution of seven cysteine residues. This structure is known as the cysteine knot and tethers together regions of the peptide as well as binding the two chains of the dimer to each other. High resolution structures are now available on proteins from three families within this group including glial derived neurotropic factor (GDNF), BMP-7 and several of the TGF-13s. Despite low similarity between some of these proteins (eg, TGF-13s and GDNF are only 13% identical) they share a strikingly similar three dimensional conformation (Fig. 1). These structural elements imbue the protein with some of its familial characteristics. These include its physico-chemical stability due to tight tethering of portions of the peptide chain via criss-crossing disulphide bonds. Much of its surfaces are coated with hydrophobic patches leading to a propensity to bind non-specifically to other proteins as well as to its self. This also causes a marked propensity for aggregation when the recombinant protein is present at high concentration.

Taschenbuch. Zustand: Neu. TGF-¿ and Related Cytokines in Inflammation | Samuel N. Breit (u. a.) | Taschenbuch | Progress in Inflammation Research | xiii | Englisch | 2012 | Birkhäuser | EAN 9783034895316 | Verantwortliche Person für die EU: Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book is a comprehensive review of the structure/function and biology of molecules belonging to the TGF-ß superfamily. Because molecules in this family have very diverse biological roles the editors have chosen to focus on the parts they play in the specific areas of inflammation and wound/fracture healing. Whilst molecules in the TGF-ß superfamily have been extensively studied, there are few, if any, publications which have taken a broad perspective on this family, most having chosen to focus on just one very small area. This book is therefore unusual in that it offers a comprehensive overview of the current state of the field, providing both in-depth and essential background material suitable for both clinicians and scientists alike.

Zustand: New. This book is a comprehensive review of the structure/function and biology of molecules belonging to the TGF-ss superfamily. Because molecules in this family have very diverse biological roles the editors have chosen to focus on the parts th.