Verlag: Royal Society of Chemistry, 2010
ISBN 10: 1849731268 ISBN 13: 9781849731263
Sprache: Englisch
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In den WarenkorbZustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
Verlag: Royal Society of Chemistry, 2010
ISBN 10: 1849731268 ISBN 13: 9781849731263
Sprache: Englisch
Anbieter: Romtrade Corp., STERLING HEIGHTS, MI, USA
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In den WarenkorbZustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
Verlag: Royal Society of Chemistry, 2010
ISBN 10: 1849731268 ISBN 13: 9781849731263
Sprache: Englisch
Anbieter: Romtrade Corp., STERLING HEIGHTS, MI, USA
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In den WarenkorbZustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
Verlag: Royal Society of Chemistry, 2010
ISBN 10: 1849731268 ISBN 13: 9781849731263
Sprache: Englisch
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Verlag: ROYAL SOCIETY OF CHEMISTRY, 2010
ISBN 10: 1849731268 ISBN 13: 9781849731263
Sprache: Englisch
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In den WarenkorbGebunden. Zustand: New. Accounts in Drug Discovery describes recent case studies in medicinal chemistry with a particular emphasis on how the inevitable problems that arise during any project can be surmounted or overcome.Über den AutorrnrnJoel C. Barrish was .
Verlag: Royal Society of Chemistry, 2010
ISBN 10: 1849731268 ISBN 13: 9781849731263
Sprache: Englisch
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In den WarenkorbBuch. Zustand: Neu. Neuware - Accounts in Drug Discovery describes recent case studies in medicinal chemistry with a particular emphasis on how the inevitable problems that arise during any project can be surmounted or overcome. The Editors cover a wide range of therapeutic areas and medicinal chemistry strategies, including lead optimization starting from high-throughput screening 'hits' as well as rational, structure-based design. The chapters include 'follow-ons' and 'next generation' compounds that aim to improve upon first-generation agents. This volume surveys the range of challenges commonly faced by medicinal chemistry researchers, including the optimization of metabolism and pharmacokinetics, toxicology, pharmaceutics and pharmacology, including proof-of-concept in the clinic for novel biological targets. The case studies include medicinal chemistry stories on recently approved and marketed drugs, but also chronicle 'near-misses', i.e. exemplary compounds that may have proceeded well into the clinic but for various reasons did not result in a successful registration. As the vast majority of projects fail prior to registration, much can be learned from such narratives. By sharing a wide range of drug discovery experiences and information across the community of medicinal chemists in both industry and academia, the Editors believe that these accounts will provide insights into the art of medicinal chemistry as it is currently practiced and will help to serve the needs of active medicinal chemists.
Verlag: Royal Society of Chemistry, 2010
ISBN 10: 1849731268 ISBN 13: 9781849731263
Sprache: Englisch
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In den WarenkorbHardcover. Zustand: Brand New. 1st edition. 379 pages. 9.75x6.50x1.00 inches. In Stock.