Badr mostafa (46 Ergebnisse)

XII, 314 p. Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Methods in Molecular Biology, 1966. Sprache: Englisch. …

Zustand: New.

Zustand: New.

PAP. Zustand: New. New Book. Shipped from UK. Established seller since 2000.

PAP. Zustand: New. New Book. Shipped from UK. Established seller since 2000.

Zustand: New.

Zustand: Hervorragend. Zustand: Hervorragend | Seiten: 328 | Sprache: Englisch | Produktart: Bücher | This volume presents valuable techniques for studying the class of ligand-activated transcription factors known as nuclear receptors. After a brief overview of the history of the field, chapters cover methods to detect the receptors and their mRNAs in various tissues, protocols to characterize nuclear receptor modulators and activities, their signaling and roles in certain pathogenesis, molecular modeling of nuclear receptor-ligand interactions, as well as the utility of informatics in the field of nuclear receptors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Nuclear Receptors: Methods and Experimental Protocols seeks to aid researchers working toward furthering ourunderstanding of these vital receptors and their role in numerous pathological conditions.…

PAP. Zustand: New. New Book. Shipped from UK. Established seller since 2000.

Zustand: New. In English.

PAP. Zustand: New. New Book. Shipped from UK. Established seller since 2000.

Zustand: New.

Zustand: New. 2015. Paperback. . . . . . Books ship from the US and Ireland.

Zustand: New. In English.

Zustand: New. In English.

Zustand: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | All three peroxisome proliferator-activated receptor (PPAR) subtypes share a high degree of structural homology while exhibiting differences in function, tissue distribution, and ligand specificity. In Peroxisome Proliferator-Activated Receptors: Discovery and Recent Advances, the authors trace the history of PPAR discovery and detail the receptor structure and its posttranslational modifications. Furthermore, endogenous ligands as well as various classes of exogenous ligands, subtype-selective, dual and pan agonists as well as antagonists, are discussed. In addition, the tissue distribution and versatile functions of PPAR subtypes in major organs are described. As PPARs play critical roles as regulators of numerous physiological as well as pathophysiological pathways, Peroxisome Proliferator-Activated Receptors: Discovery and Recent Advances aims to help researchers to develop safer and more effective PPAR modulators as therapeutic agents to treat a myriad of diseases and conditions.…

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume presents valuable techniques for studying the class of ligand-activated transcription factors known as nuclear receptors. After a brief overview of the history of the field, chapters cover methods to detect the receptors and their mRNAs in various tissues, protocols to characterize nuclear receptor modulators and activities, their signaling and roles in certain pathogenesis, molecular modeling of nuclear receptor-ligand interactions, as well as the utility of informatics in the field of nuclear receptors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Nuclear Receptors: Methods and Experimental Protocols seeks to aid researchers working toward furthering ourunderstanding of these vital receptors and their role in numerous pathological conditions.…

Zustand: New. In English.

Taschenbuch. Zustand: Neu. Nuclear Receptors | The Art and Science of Modulator Design and Discovery | Mostafa Z. Badr | Taschenbuch | xi | Englisch | 2022 | Springer International Publishing | EAN 9783030784386 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.…

Hardcover. Zustand: Brand New. 137 pages. 9.00x6.25x0.50 inches. In Stock.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Nuclear receptors are ligand activated transcription factors that control numerous biological functions. Consequently, altering activity of these receptors is proposed, and indeed documented, to affect many physiological and pathological conditions in experimental animals and humans. Thus, nuclear receptors have become a major target in the effort to treat numerous diseases.This book will shed light on and emphasize intricate processes involved in designing as well as discovering physiological and pharmacological modulators of these important proteins.World-renowned scientists will share with the reader their professional expertise and extensive experience acquired through decades working with nuclear receptors. Chapters addressthe various means and consequences of modulating nuclear receptor activity will be presented and discussed.These modulators cover a wide span of moieties ranging from synthetic chemicals to natural products. In addition, the classification of these chemicals ranges from pan agonists to selective agonists and inverse agonists to antagonists. They also include proteolytic means to obliterate the receptor in the event that modulating its activity through canonical pharmacological agents becomes less effective and/or less desirable due to anticipated or experienced toxicities. Modulation of receptor activity may also take place in the absence of a ligand or through manipulating the structure of the receptor itself by controlling posttranslational events.…

Hardcover. Zustand: Brand New. 326 pages. 10.00x7.00x0.87 inches. In Stock.

Hardcover. Zustand: Brand New. 2013 edition. 354 pages. 10.25x7.25x1.00 inches. In Stock.

Zustand: New. This book reviews the history of PPAR discovery and details receptor structure and its posttranslational modifications, discusses endogenous and exogenous ligands, the tissue distribution and versatile functions of PPAR subtypes in major organs and much more. Num Pages: 137 pages, 7 black & white tables, biography. BIC Classification: PSB; PSF. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 15. Weight in Grams: 391. . 2013. Hardback. . . . . Books ship from the US and Ireland.…

Zustand: New. A new volume in the Methods in Molecular Biology series, this book includes cutting-edge methods and advice for characterizing PPARs, reflecting their critical roles as regulators of numerous physiological as well as pathophysiological pathways. Editor(s): Badr, Mostafa Z.; Youssef, Jihan A. Series: Methods in Molecular Biology. Num Pages: 343 pages, 18 black & white tables, biography. BIC Classification: PSB; PSD. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 21. Weight in Grams: 870. . 2012. 2013th Edition. hardcover. . . . . Books ship from the US and Ireland. …

Paperback. Zustand: Brand New. 690 pages. 9.25x6.10x1.39 inches. In Stock.

Zustand: New.

Zustand: New. In English.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Nuclear receptors are ligand activated transcription factors that control numerous biological functions. Consequently, altering activity of these receptors is proposed, and indeed documented, to affect many physiological and pathological conditions in experimental animals and humans. Thus, nuclear receptors have become a major target in the effort to treat numerous diseases.This book will shed light on and emphasize intricate processes involved in designing as well as discovering physiological and pharmacological modulators of these important proteins.World-renowned scientists will share with the reader their professional expertise and extensive experience acquired through decades working with nuclear receptors. Chapters addressthe various means and consequences of modulating nuclear receptor activity will be presented and discussed.These modulators cover a wide span of moieties ranging from synthetic chemicals to natural products. In addition, the classification of these chemicals ranges from pan agonists to selective agonists and inverse agonists to antagonists. They also include proteolytic means to obliterate the receptor in the event that modulating its activity through canonical pharmacological agents becomes less effective and/or less desirable due to anticipated or experienced toxicities. Modulation of receptor activity may also take place in the absence of a ligand or through manipulating the structure of the receptor itself by controlling posttranslational events.…

Hardcover. Zustand: Brand New. 690 pages. 9.25x6.10x9.21 inches. In Stock.

PAP. Zustand: New. New Book. Shipped from UK. Established seller since 2000.