Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Taschenbuch. Zustand: Neu. Neuware - >This volume applies the BTH framework to inflammatory and autoimmune drug development. The Inflammation Path Tool scores six nodes, antigen presentation, innate activation, adaptive response, inflammatory cascade, autoimmunity loop, and intervention point, to determine how much information a catalyst will actually deliver and what the outcome distribution looks like before the data is unblinded.The MoA Tool covers every mechanism class in the sub-sector: anti-TNF, anti-IL, JAK inhibitors, T cell costimulation blockade, B cell depletion, CAR-T in autoimmune, tolerogenic vaccines, and selective cytokine modulators. The Catalyst Stack maps twenty catalyst types, from Phase 1 through biosimilar entry and label expansion, with IV expansion and crush figures calibrated to the immunology timeline. The Trade Setup chapter delivers eight named structures built for the head-to-head trial environment, the AdCom, the PDUFA, and the long-cycle franchise catalyst. Immunology rewards the trader who understands the class, not just the drug. This book connects the Biology to the trade! >Book 1: OncologyBook 2: Immunology & AutoimmuneBook 3: NeuroscienceBook 4: Rare Disease & Orphan Drugs Book 5: Cardiovascular Book 6: Metabolic Disease & Endocrinology Book 7: Gene Therapy & RNA Therapeutics Book 8: Infectious Disease & Vaccines.