In Vitro Aspects of Erythropoiesis

1. Erythropoiesis In Vitro: A Brief Introduction.- 2. Erythropoietin-Independence of Early Erythropoiesis and a Two-Regulator Model of Proliferative Control in the Hemopoietic System.- 3. In Vitro Modulation of Human Erythropoiesis by Lymphocyte-Rich Fractions of Blood.- 4. Cryogenic Preservation of Human and Murine Erythropoietic and Granulopoietic Colony-Forming Cells.- 5. Miniaturization of Methylcellulose Erythroid Colony Assay.- 6. Culture Systems In Vitro for the Assay of Erythrocytic and Megakaryocytic Progenitors.- Discussion (Chapters 1-6).- 7. Cellular and Soluble Factors Influencing the Differentiation of Primitive Erythroid Progenitor Cells (BFU-e) In Vitro.- 8. The Effect of Sustained Hypertransfusion on Hematopoiesis.- 9. Inhibitors of Erythropoiesis: Effects of Red Cell Extracts on Heme Synthesis and Erythroid Colony Formation in Human Bone Marrow Cultures.- 10. Production of Erythroid Precursor Cells in Long-Term Culture of Mouse Bone Marrow Cells.- 11. Production of Erythroid Precursor Cells (BFU) In Vitro.- Discussion (Chapters 7-11).- 12. Hormonal Modulation of Erythropoiesis In Vitro.- 13. Regulatory Mechanisms of Erythroid Stem Cell Kinetics.- 14. Hormonal Influences on Erythroid Colony Growth in Culture.- 15. A Lack of Burst-Forming Unit (BFU-e) and Lymphocyte-Mediated Suppression of Erythropoiesis in Patients with Aplastic Anemia.- 16. Pharmacological Agents and Erythroid Colony Formation: Effect of Beta-Adrenergic Agonists and Steroids.- 17. In Vitro Assessment of Similarities between Erythroid Precursors of Fetal Sheep and Patients with Polycythemia Vera.- Discussion (Chapters 12-17).- 18. Murine Erythroleukemia: Cell Surface and Cell Cycle-Related Events of Induced Differentiation.- 19. Regulation of Heme Biosynthesis in Mouse FriendVirus-Transformed Cells in Culture.- 20. Comparative Studies on Hemopoietic Stem Cell Pools in Mice after Friend (FV-P) or Rauscher Virus Infection.- 21. Studies on Erythroid Differentiation in a Wild-Type and Dimethylsulfoxide-Resistant Clone of Friend Virus-Transformed Cells: Effects of Hemin, Hemoglobin, and Erythropoietin.- 22. Induction of Uroporphyrinogen-1 Synthase Activity in Mitogen-Stimulated Lymphocytes: Deficient Induction in Acute Intermittent Porphyria Cells.- 23. Potential for Differentiation, Virus Production, and Tumorigenicity in Murine Erythroleukemic Cells Treated with Interferon.- 24. Kinetics of Erythroid and Myeloid CFU Following Rauscher Virus Infection.- Discussion (Chapters 18-24).- 25. The Role of Serum Inhibitors of Erythroid Colony-Forming Cells in the Mechanism of the Anemia of Renal Insufficiency.- 26. Modulatory Effect of Macrophages on Erythropoiesis.- Discussion (Chapters 25-26).- 27. Extrarenal Erythropoietin.- 28. In Vitro Aspects of Erythropoietin Production.- 29. Renal and Extrarenal Erythropoietin Production in Anemia.- 30. Recent Advances in Erythropoietin Physiology.- Discussion (Chapters 27-30).- Appendices 1-13.