The Role of Plant Agricultural Practices on Development of Antimicrobial Resistant Fungi Affecting Human Health: Proceedings of a Workshop Series

Antifungal use in plant agriculture is a widespread practice necessary to safeguard food safety and security. While the impact of antimicrobial resistance (AMR) is a significant global health concern, knowledge gaps exist surrounding antifungal resistance, the connection to plant agriculture, and its implications for human health.

The National Academies Forum on Microbial Threats hosted a workshop series in June 2022 exploring the role of plant agricultural practices in AMR development and implications for human health, with a focus on plant crop production. Sessions explored the magnitude of environmentally induced/selected antifungal resistance connected to plant agriculture, agricultural practices that may contribute to AMR in human pathogens, and strategies for surveillance and mitigation.This Proceedings document summarizes workshop discussions.

• Front Matter
• 1 Introduction
• 2 Fungal Pathogens in Plant and Human Health
• 3 Fungal Diseases, Antifungal Resistance, and Human Health
• 4 Fungicide Resistance in Plant Protection Use
• 5 Role of Fungicide Use in Food Safety and Security
• 6 Dimensions of Fungicide Regulations, Use Management, and Risk Assessment
• 7 Innovations in Antimicrobial Resistance Surveillance Tools and Technologies
• 8 One Health Approach to Antimicrobial Resistance and Pathogen Surveillance
• 9 Antifungal Drug Development and Stewardship in Health Care
• 10 Integrated Plant Disease Management
• References
• Appendix A: Statement of Task
• Appendix B: Workshop Agenda