Most items will be dispatched the same or the next working day. An apparently unread copy in perfect condition. Dust cover is intact with no nicks or tears. Spine has no signs of creasing. Pages are clean and not marred by notes or folds of any kind.

Bestandsnummer des Verk�ufers wbs6884662671

Verk�ufer kontaktieren

Diesen Artikel melden

Bibliografische Details

Titel

Rethinking Platinum Anticancer Drug Design: Towards Targeted and Immuno-chemotherapeutic Approaches (Springer Theses)

Verlag

Springer

Erscheinungsjahr

2018

Sprache

Englisch

ISBN-10

9811085935

ISBN-13

9789811085932

Einband

Hardcover

Zustand

Like New

Verk�uferkataloge

�ber diesen Titel

Inhaltsangabe

This thesis describes the authors' pioneering efforts in the conceptualization and implementation of combined platinum-based immuno-chemotherapeutics, which represent a significant paradigm shift from the conventional approach of directly targeting cancer. The work described has opened up a rich and largely unexplored area for platinum-based drug design, and ultimately paves the way for superior immuno-chemotherapeutics with better clinical outcome for patients. Historically, the contribution of the immune system to chemotherapy outcomes has been neglected, as anticancer drugs were believed to be immunosuppressive. However, this has been challenged by contemporary evidence suggesting that many chemotherapeutics, including platinum-based agents, stimulate the innate and/or adaptive immune system and that these "secret allies" contribute tangibly to clinical outcomes. A multi-pronged immuno-chemotherapeutic approach not only shrinks tumors, but more importantly, reactivate dormant immune responses to malignancies, eliminating residual cancer cells.

�ber die Autorin bzw. den Autor

Daniel Wong was born in Singapore and graduated with honors from the National University of Singapore (NUS) in 2011. Encouraged by a positive undergraduate research experience, he then continued to complete his doctoral studies in NUS in 2015 under the guidance of Prof. Ang Wee Han, working mainly on the immuno-modulating effects of platinum agents for cancer therapy. In 2015, he joined Nanyang Technological University as a Research Fellow under the supervision of Prof. Par Nordlund, a renowned structural biologist. There, he employed structure-based drug design techniques against molecular targets in both immuno-oncology and malaria. At the same time, he is also experimenting with new progressive methodologies for simultaneous target and ligand discovery. Apart from research, Daniel likes mentoring students because of their infectious enthusiasm and he believes that the future rests upon them. Daniel is a recipient of the Wang Gungwu Medal (2016) for best PhD thesis in the Natural Sciences in NUS and the Springer Thesis Prize (2017).

��ber diesen Titel� kann sich auf eine andere Ausgabe dieses Titels beziehen.

Anbieterinformationen

Zur Homepage des Verk�ufers

Unternehmensdaten des Verk�ufers

Revival Books Ltd
Unit 11 Hugh Business Park, Bacup Road, Waterfoot, Rossendale, BB4 7BT, United Kingdom

Gesch�ftsbedingungen und Versandinformationen

Verkaufsbedingungen

WeBuyBooks
Hall Carr Mill
Fallbarn Road
Rawtenstall
Lancashire BB4 7NX

Email: Sales@webuybooks.co.uk
Tel: 01706 227207

Company Reg. No. 07693718
VAT Number 901 5786 27

Authorised Representatives: Michael Lane and Damian Carr

Widerrufsbelehrung

Versandbedingungen

Shipping costs are based on books weighing 2.2 LB, or 1 KG. If your book order is heavy or oversized, we may contact you to let you know extra shipping is required.

Versandkosten von Vereinigtes K�nigreich nach USA

Versandkosten von Vereinigtes K�nigreich nach USA
Bestellmenge	7 bis 28�Werktage	7 bis 28�Werktage
Erster Artikel	EUR 5.94	EUR 5.94

Die Versandzeiten werden von den Verk�uferinnen und Verk�ufern festgelegt. Sie variieren je nach Versanddienstleister und Standort. Sendungen, die den Zoll passieren, k�nnen Verz�gerungen unterliegen. Eventuell anfallende Abgaben oder Geb�hren sind von der K�uferin bzw. dem K�ufer zu tragen. Die Verk�uferin bzw. der Verk�ufer kann Sie bez�glich zus�tzlicher Versandkosten kontaktieren, um einen m�glichen Anstieg der Versandkosten f�r Ihre Artikel auszugleichen.