Inhaltsangabe
Dielectrophoresis is the motion of particles caused by electrical polarization effects in inhomogenous (nonuniform) electric fields. Unlike electrophoresis, the particles do not require a net electrical charge for motion to occur and AC rather than DC fields are employed to exploit the dielectric properties of the particles. When nonuniform electric fields are created between microelectrodes, cells will redistribute themselves around the electrodes, the force holding the cells in place depending on the local electric field and on the electrical properties of cells themselves and the suspending medium. Factors controlling the effective dielectric properties of cells and microorganisms include electrical double layers associated with surface charge, the conductivity and permittivity of their membranes and cell walls, and their morphologies and structural architectures. In recent years, several laboratories have developed separation and manipulation techniques for cells and microorganisms based on dielectrophoresis, using both static and travelling AC fields. In this book, the recent advances in this field are reviewed, the basic physical factors influencing the dielectrophoretic behavior of particles are outlined, and ways in which these can be employed to achieve selective separation of cells, microorganisms and other bioparticles are described.
Reseña del editor
Dielectrophoresis is the motion of particles caused by electrical polarization effects in inhomogenous (nonuniform) electric fields. Unlike electrophoresis, the particles do not require a net electrical charge for motion to occur and AC rather than DC fields are employed to exploit the dielectric properties of the particles. When nonuniform electric fields are created between microelectrodes, cells will redistribute themselves around the electrodes, the force holding the cells in place depending on the local electric field and on the electrical properties of cells themselves and the suspending medium. Factors controlling the effective dielectric properties of cells and microorganisms include electrical double layers associated with surface charge, the conductivity and permittivity of their membranes and cell walls, and their morphologies and structural architectures. In recent years, several laboratories have developed separation and manipulation techniques for cells and microorganisms based on dielectrophoresis, using both static and travelling AC fields. In this book, the recent advances in this field are reviewed, the basic physical factors influencing the dielectrophoretic behavior of particles are outlined, and ways in which these can be employed to achieve selective separation of cells, microorganisms and other bioparticles are described.
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