Atomic spectrometry has exciting new bio-analytical horizons open to it, principally through the developments in the capabilities of ICP-MS coupled with the inventiveness of experimentalists. This is reflected in the use of the technique for ion-, capillary electrophoresis-, liquid- and gas-chromatographic separation in biological applications, as reported in this book. Traditional (environmental, semiconductor, geological and clinical) applications are also well represented. In addition, recent and future developments in sample introduction devices, multicollector sector, reaction cells and collision cells instruments, as well as co-existence, divergence and potential convergence of atomic and biomolecular mass spectrometries are discussed. Reflecting the current state of practical ICP-MS and drawing together the latest developments in the field, Plasma Source Mass Spectrometry: Current Trends and Future Developments is ideal for university researchers and laboratory practitioners. It will be of interest to all those involved in the development and application of this technique.

Plasma Source Mass Spectrometry

Current Trends and Future Developments

The Royal Society of Chemistry

Contents

Bio-analytical Applications, 
Metalloprotein Crosstalk: Quantifying Zinc Exchange Between Stable Isotopically Labeled Proteins Using Directly Coupled HPLC-ICP-MS A.Z. Mason, T.M. Potter, J. Webster and R.F. Meraz, 3, 
Speciation of Selenium Compounds by Capillary Electrophoresis ICP-MS – Evaluation of ICP-DRC-MS Detection and Different Quantification Methods J. Nurmi, G. Koellensperger, G. Stingeder, D. Metze and N. Jakubowski, 28, 
Application of ICPMS and Chromatography Based ICPMS to Studies of Metal-Protein Binding in Bioanalysis D. Gray, R. Burns, P. Brunswick, J. Le Huray, W. Chan, M. Mast, K. Allamneni and S. Sreedharan, 43, 
Determination of Total Mercury in Urine By Inductively Coupled Plasma Mass Spectrometry (ICP-MS) P. Parsons, C. Palmer, K. Caldwell and R. Jones, 59, 
Labile Arsenic Compounds in Biological Matrices, or Possible Problems Finding the Metal Species Present in Cells A. Raab, H. Hansen and J. Feldmann, 72, 
Speciation Analysis with GC-ICP-MS: Organometal Detection in Tobacco Smoke M. Elobeid, Y. Chai, D. Clarke, R. Hannigan and J. Russ, 80, 
Reaction Cells and High Resolution, 
Determination of 44Ca-Isotope Markers for Parasitoid Studies Using Dynamic Reaction Cell ICPMS B. Hattendorf H. Wanner, H. Gu, S. Dorn and D. Gunther, 91, 
Application of ICP-MS with a Hexapole Collision and Reaction Cell as an Element Selective Phosphorus Detector for Quality Control of Pharmaceuticals M. Edler, E. Busker, I. Feldmann, N. Jakubowski and C. Venzago, 99, 
Advantages of Dynamic Reaction Cell ICP-MS for Geological Analyses K. Neubauer, S. Beres, L. Dionne and D. Green, 111, 
Characterization and Production Ratio of Polyatomic Ion Interferences in Inductively Coupled Plasma Mass Spectrometry Using a High Resolution Mass Spectrometer Y. Takaku, D. Hinds and T. Shimamura, 120, 
Measurement of Actinides at Ultra-Trace Level By Double-Focusing Sector-Field ICP-MS: Instrumental Performances and Analytical Difficulties F. Pointurier, N. Baglan and Ph. Hémet, 130, 
Trends in Instrumentation, 
Biomolecular and Atomic Mass Spectrometry: Good Friends or Uncaring Strangers? A. Makarov, 145, 
Love Triangle: Trapping Fields, Ion Energy and Ion Molecule Reactions V. Baranov, D.R. Bandura and S. Tanner, 155, 
Investigation of Vaporization of Laser Ablation Generated Aerosol and Monodisperse Particles in a Dry Ar ICP Using Time-Resolved Mass Spectrometry J. Olesik and N. Casey, 164, 
Environmental Applications, 
Signal Smoothing Device for Improving Analytical Precision in LA-ICP-MS and Its Applications A. Tunheng and T. Hirata, 177, 
Metrology in Chemistry: ICP-Analysis in Environmental Science T. Prohaska, Y. Aregbe and P. Evans, 190, 
ICP-MS as Analytical Tool on Spent Nuclear Fuel Analogues Studies J. Cáceres, J. Quiñones, E. Iglesias and A. Martinez-Esparza, 207, 
Preliminary Work for the LA-ICP-MS Analysis of Carnelian Archaeological Artefacts S. Fraser, D. Polya, P. Lythgoe and T. Insoll, 213, 
Selenium Speciation in Amphibian Larvae Developing in a Coal Fly Ash Settling Basin B. Jackson, W. Hopkins, J. Unrine, J. Baionno and T. Punshon, 225, 
Speciation of Cancerostatic Platinum Compounds in a Waste Water Pilot Plant Zs. Stefánka, S. Hann, K. Lenz, G. Koellensperger, M. Fuerhacker and G. Stingeder, 235, 
Multi-collectors, 
Accurate Determination of Pt Concentrations at Ultra-low Levels (<<20Pg) in Clinical DNA Samples with High HF/PT Ratios Using the Thermo Finnigan Neptune Plasma Ionisation Multi-collector Mass Spectrometer (PIMMS) G. Nowell, D. Pearson, C. Ottley and M. Tilby, 245, 
Novel Applications of MC-ICPMS for Isotope Dilution P. Evans, C. Wolff Briche, R. Hearn and T. Catterick, 259, 
Solution and Laser Ablation Analysis of Sulphur Isotopes with the Neptune High Resolution Multi-collector ICP-MS (MC-ICP-MS): Application to Diffusive Gradients in Thin Films D. Bellis, G. Nowell, C. Ottley, D. Pearson and W. Davison, 268, 
Accuracy and Precision in Plasma Ionisation Multi-collector Mass Spectrometry: Constraints from Neodymium and Hafnium Isotope Measurements D. Pearson and G. Nowell, 284, 
Semiconductors, 
Application of ICP-MS Technology to Semiconductor Manufacturing J.-M. Collard and Y. Kishi, 317, 
Author Index, 334, 
Subject Index, 337,