Osteoimmunology

Joseph Lorenzo

Verlag: ACADEMIC PRESS Okt 2015, 2015
ISBN 10: 0128005718 / ISBN 13: 9780128005712
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Neuware - Englisch. Buchnummer des Verkäufers

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Reseña del editor: Osteoimmunology: Interactions of the Immune and Skeletal Systems, Second Edition, explores the advancements that have been made in the field during the last 40 years, including valuable information on our understanding of the interactions between hematopoietic, immune, and bone cells, now known as the field of osteoimmunology. This comprehensive work offers the most extensive summaries of research trends in the field and their translation into new therapeutics. Early chapters deal with the development of osteoblasts, osteoclasts, hematopoietic stem cells, T and B-lymphocytes, and communications between these cellular elements, while later sections contain discussions of the signaling pathways by which RANKL influences osteoclast development and function. Subsequent chapters explore the effects that estrogen has on bone and the immune system, the development of pathologic conditions, and the growing research around osteoporosis, Paget's disease, the genetics of bone disease, and bone cancer metastasis. * Explains the intricate interaction between the immune system and bone* Features detailed discussions of the key cellular and molecular mechanisms governing the homeostasis of the individual systems* Facilitates greater understanding of osteoimmunologic networks, their environments, and how this understanding leads to better treatments for human diseases involving both systems

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Titel: Osteoimmunology
Verlag: ACADEMIC PRESS Okt 2015
Erscheinungsdatum: 2015
Einband: Buch
Zustand: Neu

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Pietschmann, Peter:
Verlag: Cham, Springer International Publishing, 2016. (2016)
ISBN 10: 3319342363 ISBN 13: 9783319342368
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Buchbeschreibung Cham, Springer International Publishing, 2016., 2016. 2nd ed. Molecular Mechanisms and Clinical Applications. X, 328 p. Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Artikel-Nr. 32822AB

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Peter Pietschmann
Verlag: Springer-Verlag Gmbh Aug 2016 (2016)
ISBN 10: 3319342363 ISBN 13: 9783319342368
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Buchbeschreibung Springer-Verlag Gmbh Aug 2016, 2016. Buch. Buchzustand: Neu. 242x164x22 mm. Neuware - This fully updated and extended second edition provides a comprehensive overview on the basic concepts of the rapidly developing field of osteoimmunology and also offers in-depth insights into the molecular mechanisms of bone diseases. Clinical data is presented and put into context with the latest research findings. This second edition in addition discusses the latest topics in transplantation immunology. The book addresses scientists and physicians working in immunology, pathophysiology and osteology. 328 pp. Englisch. Artikel-Nr. 9783319342368

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Yongwon Choi
Verlag: Springer-Verlag Gmbh Nov 2009 (2009)
ISBN 10: 1441910492 ISBN 13: 9781441910493
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Buchbeschreibung Springer-Verlag Gmbh Nov 2009, 2009. Buch. Buchzustand: Neu. 240x163x20 mm. Neuware - It has only recently been appreciated that the immune and skeletal systems have major interactions. It is now well documented that osteoclasts, which are important cellular mediators of skeletal homeostasis, are derived from hematopoietic precursors that also give rise to immune cells. In addition, numerous cytokines that were first shown to regulate immune cell function have also been demonstrated to regulate bone cells and influence skeletal health. Conversely, products of bone cells appear critical for the engraftment of marrow in bone, the normal development of the hematopoietic and immune systems and provide niche for long-term memory B and T cells. 122 pp. Englisch. Artikel-Nr. 9781441910493

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Yongwon Choi
Verlag: Springer-Verlag Gmbh Okt 2007 (2007)
ISBN 10: 0387720081 ISBN 13: 9780387720081
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Buchbeschreibung Springer-Verlag Gmbh Okt 2007, 2007. Buch. Buchzustand: Neu. 242x210x14 mm. Neuware - A Key Regulator of Postnatal Skeletal Remodeling.- Ectodomain Shedding of Receptor Activator of NF-KB Ligand.- The Negative Role Of Ids In Osteoclastogenesis.- Functional Genetic and Genomic Analysis of Modeled Arthritis.- Dexamethsone Suppresses Bone Formation via the Osteoclast.- Immunologic Regulation Of Bone Development.- Pth Regulates The Hematopoietic Stem Cell Niche In Bone.- Regulation Of Hematopoietic Stem Cells In The Osteoblastic Niche.- The Chemokine Cxcl12 And Regulation Of Hsc And Lymphocyte Development In The Bone Marrow Niche.- Osteoclast Precursor Cells.- Interaction with estrogen receptors as treatment of arthritis and osteoporosis.- Novel Signaling Pathways And Therapeutic Targets In Osteoclasts.- The Enigmatic Function of TREM-2 in Osteoclastogenesis.- Role of cell-matrix interactions in osteoclast differentiation.- Positive and negative roles of IL-6, STAT3 and SOCS3 in inflammatory arthritis.- Control of Osteoclast activity and bone loss by IKK subunits: new targets for therapy.- Targeting Osteoporosis And Rheumatoid Arthritis By Active Vaccination Against Rankl.- RANKL Inhibition: From Mice to Men (and Women). 156 pp. Englisch. Artikel-Nr. 9780387720081

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