New Concepts of Antiviral Therapy. Dieser Artikel ist nicht verfügbar.New Concepts of Antiviral Therapy

Antiviral drugs are important tools for treatment or prevention of viral infections. These drugs were first used for monotherapy, but nowadays combinations of antiviral agents are often part of a standard treatment as evidenced by e.g. HAART (highly active antiretroviral therapy). However, in almost every case of antiviral therapy, drug resistant viruses appear. In addition, the low oral bioavailability, toxicity and the number of severe side effects still pose significant problems. All of the latter issues limit the clinical usefulness and drive the need for improved antiviral strategies. These strategies include new drugs and targets, novel modes of action, vector-based treatments and even the block of defined genes by inhibiting mRNA formation (siRNA).

Highlights of this book include the discussion of:

- novel, promising compounds

- concepts of therapy for new/emerging viruses

- managing drug resistance

- new therapeutic strategies

This book presents an overview of the most recent developments. Contributions were carefully selected to ensure quality coverage by acknowledged experts over a wide spectrum and should prove to be of great value to students and serve as a compendium for R and D and educational professionals.

Antiviral drugs are vital, but imperfect tools for treatment and prevention of viral infections. Undesirable effects, from drug resistant viruses to low oral bioavailability, toxicity and severe side effects limit clinical usefulness. All these issues drive the need for improved antiviral strategies. This book offers an up-to-date review of new drugs and targets, novel modes of action, vector-based treatments and even the blocking of defined genes by inhibiting mRNA formation (siRNA). Highlights include the discussion of novel, promising compounds; concepts of therapy for new/emerging viruses; managing drug resistance; new therapeutic strategies. Contributions were carefully selected to ensure quality coverage by acknowledged experts over a wide spectrum and will be of great value to students and serve as a compendium for R&D and educational professionals.