Polycystic ovary syndrome (PCOS) is one of the most common female endocrine disorders, but there is strong evidence that it can to a large degree be classified as a genetic disease.It is thought to be one of the leading causes of female subfertility and the most frequent endocrine problem in women of reproductive age.Women with PCOS are more insulin resistant, and up to 40% of these patients have impaired glucose tolerance. They are at an increased (3–7 times) risk of developing early-onset type 2 diabetes, the risk being greater in obese PCOS patients and those with a family history of type 2 diabetes.Insulin plays both direct and indirect roles in the pathogenesis of androgen excess in PCOS.A highly polymorphic stretch of DNA lying 360 bp upstream of the initiation of transcription of the INS gene called Variable Number of Tandem Repeats (VNTR). There are three classes of (VNTR) in the insulin gene (class I ,class II and class III) .Any mutations in this region may be effect on insulin gene (INS) expressions .

Rese�a del editor

Polycystic ovary syndrome (PCOS) is one of the most common female endocrine disorders, but there is strong evidence that it can to a large degree be classified as a genetic disease.It is thought to be one of the leading causes of female subfertility and the most frequent endocrine problem in women of reproductive age.Women with PCOS are more insulin resistant, and up to 40% of these patients have impaired glucose tolerance. They are at an increased (3-7 times) risk of developing early-onset type 2 diabetes, the risk being greater in obese PCOS patients and those with a family history of type 2 diabetes.Insulin plays both direct and indirect roles in the pathogenesis of androgen excess in PCOS.A highly polymorphic stretch of DNA lying 360 bp upstream of the initiation of transcription of the INS gene called Variable Number of Tandem Repeats (VNTR). There are three classes of (VNTR) in the insulin gene (class I ,class II and class III) .Any mutations in this region may be effect on insulin gene (INS) expressions .

��ber diesen Titel� kann sich auf eine andere Ausgabe dieses Titels beziehen.

Anbieterinformationen

Hello! Ria Christie Collections is an online venture that was initially set up in 2012 to sell books. We do not have a physical high street store. We are professional online booksellers. We only sell brand new books in perfect condition that we source from various suppliers and the publishers. Primarily, our aim is to provide an excellent service to all our customers. We always work as a team to achieve this. Our other objectives are to: 1. Ensure that all our products reach their destination quickly in a safe and secure manner 2. Answer to all our customer queries within 24 hours 3. Ensure that our customers are happy with their purchases 4. Provide all the items at a competitive price 5. Always listen to our customers Ria Christie Collections is not a registered company. It is a Sole Trader venture. Other key information is shown below: Contact Person Name: Rakesh Luchmun (Mr) Storefront Name: Ria Christie Collections Place of Establishment Address: Suite B; ARUN House; ARUN Building Arundel Road Uxbridge UB8 2RR United Kingdom E-Mail Address: riachristie@hotmail.co.uk VAT Number: GB 160 5650 25 We always work hard and aim to comply with all of Abebooks Policies. If you have any issues, please do not hesitate to write to us whether before or after a purchase. We promise to reply to you promptly and, in any case, within 24 hours. Thank you kindly! Yours sincerely Mr Rakesh Luchmun (Founder) and the Ria Christie Collections Team

Zur Homepage des Verk�ufers

Unternehmensdaten des Verk�ufers

Ryefield Investments Limited
175 Pield Heath Road, Uxbridge, UB8 3NL, United Kingdom

Gesch�ftsbedingungen und Versandinformationen

Verkaufsbedingungen

All Returns and Refund are as per Abebooks policies.

Widerrufsbelehrung

Versandbedingungen

Orders usually ship within 2 business days. If your book order is heavy or oversized, we may contact you to let you know extra shipping is required. Thank you!

Versandkosten von Vereinigtes K�nigreich nach Deutschland

Versandkosten von Vereinigtes K�nigreich nach Deutschland
Bestellmenge	5 bis 10�Werktage	5 bis 10�Werktage
Erster Artikel	EUR 5.69	EUR 5.69

Die Versandzeiten werden von den Verk�uferinnen und Verk�ufern festgelegt. Sie variieren je nach Versanddienstleister und Standort. Sendungen, die den Zoll passieren, k�nnen Verz�gerungen unterliegen. Eventuell anfallende Abgaben oder Geb�hren sind von der K�uferin bzw. dem K�ufer zu tragen. Die Verk�uferin bzw. der Verk�ufer kann Sie bez�glich zus�tzlicher Versandkosten kontaktieren, um einen m�glichen Anstieg der Versandkosten f�r Ihre Artikel auszugleichen.