The Molecular Basis of Cancer

This comprehensive, new reference will provide clinicians and other professionals who manage cancer patients, the scientific tools necessary to fully understand the disease and its therapy. The sequence of chapters leads the reader from the basic mechanisms of malignant transformation of cells, to the molecular and biological features of tumour growth and metastasis in the body, then to the molecular abnormalities found in common types of cancer, and finally to the molecular basis for new approaches to cancer therapy. The text reveals the very latest scientific research in cancer treatment and supplies the foundation for new approaches to evaluation and therapy of cancer patients. OUTSTANDING FEATURES: Four leading investigators and educators in the field, plus 37 contributing authorities, combine their expertise to clearly explain the discoveries that are revolutionising the understanding of the malignant transformation, pathogenesis and treatment of cancer. Complete examples of clinical interventions in cancer treatment, utilising new drugs, biological agents, engineered molecules and gene therapies help the practitioner to understand and evaluate the products of the biotechnology revolution occurring in academic centers and the pharmaceutical industry. Numerous illustrations and tables of molecular diagrams and more, clarify important points.