Medicinal Natural Products : A Biosynthetic Approach. Dieser Artikel ist nicht verfügbar.Medicinal Natural Products : A Biosynthetic Approach

Pharmacologically active natural products from plants, microorganisms and animals have been used for centuries in the treatment of diseases. Within the science of pharmacognosy early herbal remedies and animal extracts have been evaluated and analyzed to produce both modified (semi-synthetic) extracts and synthetic analogues. This textbook provides an introduction to natural products in medicine from a biosynthetic point of view, rather than the more usual natural product class or activity viewpoint. The book provides coverage of plant, microbial and animal products, with the main text supplemented by short, boxed essays covering important classes of compounds with detailed explanations.

Medicinal Natural Products A Biosynthetic Approach Paul M Dewick Department of Pharmaceutical Sciences, University of Nottingham, UK It has been estimated that up to 70% of the world′s population is reliant on natural materials for medical treatment and in the light of the continued search for new drugs by today′s pharmaceutical industry there is currently renewed interest in pharmacologically active natural products, be they from microorganisms, animals or plants. Written for undergraduate students of pharmacy, medicinal chemistry, pharmacognosy, phytochemistry, chemistry and indeed all those with an interest in natural products, Medicinal Natural Products provides a comprehensive introduction to this subject from a biosynthetic point of view. Building on fundamental chemical principles and demonstrating a unique integration of plant, microbial and animal natural products in one volume, Paul Dewick guides the reader through a wealth of diverse natural metabolites used in medicine. Sources, production methods, use as drugs and modes of action are all covered, together with semi–synthetic derivatives and synthetic analogues developed from natural product templates. Medicinal Natural Products includes extensive use of chemical schemes with annotated mechanistic explanations and is highly cross–referenced to emphasize the links and similarities among natural products. Written in a user–friendly style, this is a stimulating textbook for today′s students, and an ideal starting point for project and dissertation work.