In recent years there has been an increase in the need for transplantation, but the number of donor livers available has increased only slightly, despite intensive public relations activities. The development and application of cell therapy for patients with liver disease could present a significant enhancement of the therapeutic options. Editor(s): Gupta, S.; Jansen, P.L.M. (University Hospital, Groningen, Netherlands); Klempnauer, J. (Gastroenterologie/Hepatologie, Medizinische Hochschule Hannover, Germany); Manns, M. P. Series: Falk Symposium. Num Pages: 190 pages, biography. BIC Classification: MJJ; MNG. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly. Dimension: 234 x 156 x 12. Weight in Grams: 990. . 2002. Hardback. . . . . Books ship from the US and Ireland.

Bestandsnummer des Verk�ufers V9780792387763

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Titel: Hepatocyte Transplantation
Verlag: Kluwer Academic Publishers
Erscheinungsjahr: 2002
Sprache: Englisch
ISBN-10: 0792387767
ISBN-13: 9780792387763
Einband: Hardcover
Zustand: New

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In recent years there has been an increasing need for transplantation, but the number of donor livers available has increased only slightly, despite intensive public relations activities. New concepts in the field of transplantation, for instance the transplantation of living donor organs or the splitting of organs, are urgently required, to safeguard the treatment of patients with severe liver disease. The development and clinical application of cell therapy for patients with liver disease could soon present a significant enhancement of the therapeutic options. The aim of such cell therapy is to repair or improve the biological function of the chronically and acutely damaged liver. Even though systematic trials are not available, individual case reports and small series already show promising clinical results.

Present concepts of cell therapy for liver diseases based on the use of primary hepatocytes have recently been considerably extended through new data on the biology of stem cells. The adult haematopoetic stem cell as a pool for hepatocyte grafts - what would be the perspectives for the clinical application?

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