A very remarkable collection of essays. Strongly recommended to workers in this area. (International Statistical Review, 1 October 2013) I would highly recommend this book as a useful guide for the students and practitioners of systems biology. (Science Progress, 1 September 2012) This handbook will be a key resource for researchers practising systems biology, and those requiring a comprehensive overview of this important field. (Zentralblatt MATH, 2012)

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