Durante os �ltimos anos, a doen�a periodontal tornou-se um grave problema de sa�de oral em todo o mundo. P. gingivalis est� h� muito implicado como um agente etiol�gico importante no aparecimento e progress�o da periodontite. As fimbriae, um importante factor de virul�ncia de P. gingivalis, foram classificadas em seis gen�tipos (I-V, e Ib), com base na diversidade gen�mica do gene fimA. Este livro baseia-se num trabalho de investiga��o que sugere uma estreita associa��o entre a actividade da doen�a periodontal e o gen�tipo P. gingivalis tipo II fimA. Com base nesta associa��o, a detec��o do gen�tipo fimA tipo II pode ser recomendada como um marcador para o diagn�stico de doen�as periodontais, bem como a sua actividade de doen�a. Este livro ser� de interesse para investigadores, estudantes de gradua��o e p�s-gradua��o em microbiologia, imunologia, assim como medicina molecular e odontologia.

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