Titel: Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 4 (Advances in Experimental Medicine & Biology)
Verlag: Springer
Ver�ffentlichungsdatum: 2000
Sprache: Englisch
ISBN-10: 0306461382
ISBN-13: 9780306461385
Bindung: Hardcover
Zustand: New

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Inhaltsangabe

Regulation of Eicosanoid Enzymes. Cyclooxygenases. Phospholipases/PAF. Receptors. Leukotrienes and Lipoxins. Isoprostanes. Signal Transduction. Bioactive Lipids in Inflammation. Linoleic and Linolenic Acids. Anandamide and Other Bioactive Lipids. Apoptosis. Cancer Prevention and Treatment. Bioactive Lipids in Non-Mammalian Cells. Contributors. Index.

Rese�a del editor

Since their discovery over sixty years ago, eicosanoids have come to represent a diverse family of bioactive lipid modulators, including prostaglandins, thromboxanes, leukotrienes, lipoxins, isoprostanes, hepoxilins, hydroxy acids, epoxy and hydroxy fatty acids. This book contains conference presentations regarding the regulation of eicosanoid enzymes and, in particular, cyclooxygenases, lipoxygenases, and phospholipases. In addition, recent evidence over the last seven years has led to the identification of a number of receptors for these bioactive lipids. The new field of isoprostanes is also represented. It has become increasingly evident that eicosanoids play a critical role in signal transduction, both in normal cells and in pathological processes. These aspects are discussed in relation to cellular events, such as apoptosis, angiogenesis, and cancer prevention and treatment.

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