DNA Replication and Human Disease

This is a second edition of DNA Replication in Eukaryotic Cells, published in 1996. This up-to-date monograph provides a broad account of DNA replication and related functions such as DNA repair and protein phosphorylation, as well as a review of recent advances in understanding the complex gene and protein interactions that underpin this essential cellular function. The new edition not only summarizes the many advances in our understanding of DNA replication in eukaryotic cells that have occurred during the past decade, but also will stimulate thinking about the relationships between DNA replication, human disease, and targeted therapeutics.